219566-68-4

Basic information

• Product Name: (R)-4-((1S,2R)-1,2-Bis-benzyloxy-3-hydroxy-propyl)-4-hydroxy-dihydro-furan-2-one
• Synonyms: (R)-4-((1S,2R)-1,2-Bis-benzyloxy-3-hydroxy-propyl)-4-hydroxy-dihydro-furan-2-one
• CAS NO: 219566-68-4
• Molecular Weight: 372.418
• Mol File: 219566-68-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-((1S,2R)-1,2-Bis-benzyloxy-3-hydroxy-propyl)-4-hydroxy-dihydro-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-((1S,2R)-1,2-Bis-benzyloxy-3-hydroxy-propyl)-4-hydroxy-dihydro-furan-2-one(219566-68-4)
• EPA Substance Registry System: (R)-4-((1S,2R)-1,2-Bis-benzyloxy-3-hydroxy-propyl)-4-hydroxy-dihydro-furan-2-one(219566-68-4)

Safety Data

• Hazardous Substances Data: 219566-68-4(Hazardous Substances Data)

Upstream product

• 1055030-35-7 1-(tert-butyl-diphenyl-silanyloxy)-4-(tert-butyl-diphenyl-silanyloxymethyl)-hept-6-ene-2,3,4-triol 
• 100-39-0 benzyl bromide 
• 551-84-8 xylulose 

Downstream Products

• 189328-24-3 3,4-bis(benzyloxy)-1,7-dioxaspiro[4.4]nonan-8-one 

Relevant articles and documents

A formal synthesis of the syributins and secosyrins and a synthetic approach toward the syringolides

The indium-mediated allylation of a protected derivative of D-xylulose in aqueous THF is highly diastereoselective. The obtained product has been converted in four steps into a spiro lactone previously transformed into syributins and secosyrins. This remarkably short reaction sequence constitutes therefore a formal synthesis of these compounds and provides also a promising synthetic approach towards the syringolides.