21958-32-7Relevant academic research and scientific papers
Palladium catalyzed chemo- and site-selective C-H acetoxylation and hydroxylation of oxobenzoxazine derivatives
Bakthadoss, Manickam,Vijay Kumar, Polu,Kumar, Ravan,Agarwal, Vishal
supporting information, p. 4465 - 4469 (2019/05/16)
An efficient protocol for the introduction of acetoxy and hydroxy functionalities on unactivated aryl sp2 carbons of oxobenzoxazine derivatives via an ortho-C-H activation reaction using a palladium catalyst has been developed for the first tim
Gelation-induced enhanced fluorescence emission from organogels of salicylanilide-containing compounds exhibiting excited-state intramolecular proton transfer: Synthesis and self-assembly
Nayak, Manoj Kumar,Kim, Byung-Hwa,Kwon, Ji Eon,Park, Sanghyuk,Seo, Jangwon,Chung, Jong Won,Park, Soo Young
experimental part, p. 7437 - 7447 (2010/09/11)
Self-assembly structure, stability, hydrogen-bonding interaction, and optical properties of a new class of low molecular weight organogelators (LMOGs) formed by salicylanilides 3 and 4 have been investigated by fieldemission scanning electron microscopy (
Studies on Quinazolinones as Dual Inhibitors of Pgp and MRP1 in Multidrug Resistance
Wang, Shouming,Ryder, Hamish,Pretswell, Ian,Depledge, Paul,Milton, John,Hancox, Timothy C.,Dale, Ian,Dangerfield, Wendy,Charlton, Peter,Faint, Richard,Dodd, Rory,Hassan, Stephanie
, p. 571 - 574 (2007/10/03)
The syntheses and SAR studies of various quinazolinone compounds are described for the dual inhibition of Pgp and MRP1 in multidrug resistance.
Synthesis and luminescence properties of 3,1-benzoxazine and quinazoline derivatives
Ivakhnenko,Kharlanov,Maksimenko,Knyazhanskii
, p. 123 - 127 (2007/10/03)
2-(2-Hydroxyphenyl)-3,1-benzoxazin-4-one and 2-(2-hydroxyphenyl)-3-isopropylquinazolin-4(3H)-one were synthesized, and their structure was studied by NMR, IR, and UV spectroscopy. Absorption and luminecence properties of these compounds in various solvents were studied by stationary UV and luminescence spectroscopy. They were shown to exist in two isomeric forms (trans and cis) due to rotation about the C-C bond. Excitation at the absorption band of the cis structure with intramolecular hydrogen bond results in intramolecular proton transfer in the singlet excited state with formation of nonpolar oxo form which is responsible for fluorescence with an anomalous Stokes shift. * This study was financially supported by the Russian Foundation for Basic Research (project no. 97-03-32017a).
Synthesis and evaluation of 2-aryl-4H-3,1-benzoxazin-4-ones as C1r serine protease inhibitors
Gilmore, John L.,Hays, Sheryl J.,Caprathe, Bradley W.,Lee, Chitase,Emmerling, Mark R.,Michael, Walter,Jaen, Juan C.
, p. 679 - 682 (2007/10/03)
A series of 2-aryl-4H-3,1-benzoxazin-4-ones have been synthesized and tested for inhibitory activity against C1r serine protease. Compounds were found that were equipotent and more selective than the reference compound FUT-175.
