219606-74-3

Basic information

• Product Name: (3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal
• Synonyms: (3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal
• CAS NO: 219606-74-3
• Molecular Weight: 366.573
• Mol File: 219606-74-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal(219606-74-3)
• EPA Substance Registry System: (3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal(219606-74-3)

Safety Data

• Hazardous Substances Data: 219606-74-3(Hazardous Substances Data)

Upstream product

• 203926-55-0 (2R,3S)-1-[(4-methoxyphenyl)methoxy]-2-methyl-5-hexen-3-ol 
• 160238-46-0 (2R)-3-(4-methoxybenzyloxy)-2-methyl-1-propanal 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 219606-73-2 tert-Butyl-{(S)-1-[(R)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-but-3-enyloxy}-dimethyl-silane 

Downstream Products

• 162600-54-6 arenastatin A 
• 162600-54-6 (E)-(3S,10R,16S)-3-Isobutyl-10-(4-methoxy-benzyl)-16-[(S)-1-((2S,3R)-3-phenyl-oxiranyl)-ethyl]-1,4-dioxa-8,11-diaza-cyclohexadec-13-ene-2,5,9,12-tetraone 
• 245125-91-1 tert-butyl (5S,6R)-5-[(2S)-2-[3-[(2R)-2-(tert-butoxycarbonylamino)-3-(3-chloro-4-methoxyphenyl)propionylamino]propionyloxy]-4-methylpentanoyloxy]-6-methyl-8-phenylocta-2(E),-7(E)-dienoate 
• 219606-86-7 tert-butyl (5S,6R)-5-[(2S)-2-[3-[(2R)-2-tert-butoxycarbonylamino-3-(4-methoxyphenyl)-propionylamino]propionyloxy]-4-methylpentanoyloxy]-6-methyl-8-phenylocta-2(E),7(E)-dienoate 
• 219606-79-8 tert-butyl (2E,5S,6R,7E)-5-{[tert-butyl(dimethyl)silyl]oxy}-6-methyl-8-phenylocta-2,7-dienoate 
• 245125-92-2 tert-butyl (5S,6R)-5-[(2S)-2-[(2R)-3-[(2R)-2-tert-butoxycarbonylamino-3-(4-methoxyphenyl)-propionylamino]-2-methylpropionyloxy]-4-methylpentanoyloxy]-6-methyl-8-phenylocta-2(E),7(E)-dienoate 
• 178977-57-6 tert-butyl (5S,6R,2E,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoate 
• 182486-25-5 tert-butyl (5S,6R)-5-[(2S)-2-[(2R)-3-[(2R)-2-tert-butoxycarbonylamino-3-(3-chloro-4-methoxyphenyl)propionylamino]-2-methylpropionyloxy]-4-methylpentanoyloxy]-6-methyl-8-phenylocta-2(E),7(E)-dienoate 
• 124689-65-2 cryptophycin-1 
• 124689-64-1 cryptophycin C 
• 162600-54-6 arenastatin A 
• 162600-54-6 cryptophycin-24 
• 162473-78-1 desepoxyarenastatin A 
• 155645-51-5 Cryptophycin 4 

Relevant articles and documents

Total Synthesis of Cryptophycins-1, -3, -4, -24 (Arenastatin A), and -29, Cytotoxic Depsipeptides from Cyanobacteria of the Nostocaceae

A convergent synthesis of cryptophycins has been developed in which (5S,6R)-5-hydroxy-6-methyl-8-phenylocta-2(E),7(E)-dienoic acid (A) is coupled with an amino acid segment (B). Two stereo-selective routes to A are described, the first employing allylatio