(3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal

Base Information

Chemical Name:(3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal
CAS No.:219606-74-3
Molecular Formula:C₂₀H₃₄O₄Si
Molecular Weight:366.573
Hs Code.:

Synonyms:(3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal

Suppliers and Price of (3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal

There total 4 articles about (3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 219606-73-2
tert-Butyl-{(S)-1-[(R)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-but-3-enyloxy}-dimethyl-silane

: 219606-74-3
(3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal

Guidance literature:: With sodium periodate; osmium(VIII) oxide; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; for 20h;
DOI:10.1021/jo9907585

Reference yield:

: 160238-46-0
(2R)-3-(4-methoxybenzyloxy)-2-methyl-1-propanal

: 219606-74-3
(3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / tin tetrachloride / CH₂Cl₂ / 1 h / -100 °C

2: 95 percent / imidazole / dimethylformamide / 18 h / 20 °C

3: 77 percent / OsO₄; NaIO₄ / tetrahydrofuran; H₂O; 2-methyl-propan-2-ol / 20 h / 20 °C

With 1H-imidazole; sodium periodate; osmium(VIII) oxide; tin(IV) chloride; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol; 1: allylation / 2: Etherification / 3: Oxidation;
DOI:10.1021/jo9907585

Reference yield:

: 203926-55-0
(2R,3S)-1-[(4-methoxyphenyl)methoxy]-2-methyl-5-hexen-3-ol

: 219606-74-3
(3S,4R)-3-tert-butyldimethylsilanyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / imidazole / dimethylformamide / 18 h / 20 °C

2: 77 percent / OsO₄; NaIO₄ / tetrahydrofuran; H₂O; 2-methyl-propan-2-ol / 20 h / 20 °C

With 1H-imidazole; sodium periodate; osmium(VIII) oxide; In tetrahydrofuran; water; N,N-dimethyl-formamide; tert-butyl alcohol; 1: Etherification / 2: Oxidation;
DOI:10.1021/jo9907585