219646-79-4Relevant academic research and scientific papers
Natural zinniol derivatives from Alternaria tagetica. Isolation, synthesis, and structure-activity correlation.
Gamboa-Angulo, M Marcela,Escalante-Erosa, Fabiola,Garcia-Sosa, Karlina,Alejos-Gonzalez, Fatima,Delgado-Lamas, Guillermo,Pena-Rodriguez, Luis M
, p. 1053 - 1058 (2002)
Two novel phytotoxins, 8-zinniol methyl ether (5) and 8-zinniol acetate (6), in addition to 6-(3',3'-dimethylallyloxy)-4-methoxy-5-methylphthalide (2), 5-(3',3'-dimethylallyloxy)-7-methoxy-6-methylphthalide (3), and the novel metabolites 8-zinniol 2-(phenyl)ethyl ether (4) and 7-zinniol acetate (7) have been identified as natural zinniol derivatives from the organic crude extract of Alternaria tagetica culture filtrates. Using zinniol as the starting material, phytotoxin 5 was synthesized, together with a number of synthetic intermediates (8-13). Both natural and synthetic zinniol derivatives were evaluated in the leaf-spot bioassay against marigold leaves (Tagetes erecta).
