219677-72-2Relevant academic research and scientific papers
Synthesis of peptidinol adenylates
Kreimeyer, Annett,Marliere, Philippe
, p. 2339 - 2350 (2007/10/03)
Peptidinol adenylates were assembled by condensing the carboxyl group of N-blocked peptides with the alkylamino group of leucinol 5' adenosine phosphodiester. The latter was prepared as protected precursor from adenosine and leucinol by phosphite chemistry. The title compounds, which mimic aminoacyl adenylates, are designed to penetrate microorganisms via peptide permeases and to interfere with genetic translation.
