219739-79-4Relevant academic research and scientific papers
Photosensitive compound and preparation method and application thereof
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Paragraph 0071; 0089-0091, (2021/06/09)
The invention discloses a photosensitive compound and a preparation method and application thereof, and relates to the technical field of protein nucleic acid co-immobilization, the photosensitive compound is a polyacrylamide compound, and comprises a tetrazole group and a furan group; the compound is prepared from the following raw materials: N-(3-aminopropyl) tert-butyl carbamate, methacryloyl chloride furan-2-yl boric acid, [hydroxyl (phenyl)-lambda 3-iodo] 4-methyl benzene sulfonate and the like. Protein and nucleic acid co-immobilization electrophoresis gel can be prepared, and protein and nucleic acid in single cells or multiple cells can be quantitatively or semi-quantitatively detected; the compound can also be used for microchip electrophoresis mobility analysis, western blotting, nucleic acid blotting hybridization, single-cell western blotting, single-cell northern/source blotting hybridization or capillary electrophoresis western blotting. The protein and nucleic acid co-immobilization gel can be used for simultaneously immobilizing protein and nucleic acid in situ to research the interaction between the protein and DNA (Deoxyribose Nucleic Acid).
COMPOSITIONS AND ASSOCIATED METHODS FOR RADIOISOTOPE-BINDING MICROPARTICLES
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, (2014/09/29)
The present disclosure relates to polymeric materials that may be labeled with a radioisotope, to processes for producing the labeled polymeric material, and to methods of using the materials in analytical and therapeutic applications. Specifically, the disclosure relates to injectable and implantable microparticles, such as microspheres, which are associated with radioisotopes such that the microparticles are both therapeutic and detectable. The radioisotope-containing microparticles are useful for embolization and other therapeutic medical applications.
Photoactivatable nucleic acids
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, (2008/06/13)
A photoactivatable nucleic acid derivative composition in which one or more photoreactive group(s) are bound to a natural or synthetic nucleic acid. The photoreactive groups can be bound to the nucleic acid before, during or after its formation, and can t
Medicament incorporation matrix
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, (2008/06/13)
A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device positioned in vivo. Once crosslinked, the coating composition provides a gel matrix adapted to contain the medi
Target molecule attachment to surfaces
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, (2008/06/13)
Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of covalently binding to the target molecule. Optionally, the composition c
PHOTOACTIVATABLE NUCLEIC ACID DERIVATIVES
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, (2008/06/13)
A photoactivatable nucleic acid derivative composition in which one or more photoreactive group(s) are bound to a natural or synthetic nucleic acid. The photoreactive groups can be bound to the nucleic acid before, during or after its formation, and can t
TARGET MOLECULE ATTACHMENT TO SURFACES
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, (2008/06/13)
Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of covalently binding to the target molecule. Optionally, the composition c
Reagent and method for attaching target molecules to a surface
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, (2008/06/13)
Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of attracting the target molecule as well as groups capable of covalently binding to the target molecule, once attracted. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface.
