219745-25-2Relevant academic research and scientific papers
Radical C(sp3)-H Heck-type Reaction of N-Alkoxybenzimidoyl Chlorides with Styrenes to Construct Alkenols
Fang, Di,Zhang, Yidan,Chen, Yiyun
supporting information, p. 2050 - 2054 (2022/03/17)
We report the first radical C(sp3)-H Heck-type reaction of aliphatic alcohols for selective δ- and ?-alkenol synthesis by photoredox catalysis. N-Alkoxybenzimidoyl chlorides are developed as novel alkoxyl radical precursors with tunable redox potentials. Various alkenols can be constructed by the inert C(sp3)-H Heck-type reaction of 4-cyano-N-alkoxybenzimidoyl chlorides with styrene derivatives under redox-neutral conditions, which can be performed on the gram scale and can be easily derivatized.
Copper-catalyzed remote sp3 C-H chlorination of alkyl hydroperoxides
Kundu, Rituparna,Ball, Zachary T.
supporting information; experimental part, p. 2460 - 2463 (2010/07/05)
A copper-catalyzed methodology to functionalize remote sp3 C-H bonds in alkyl hydroperoxides is presented. The atom-transfer chlorination utilizes simple ammonium chloride salts as the chlorine source, and the internal redox process requires no external redox reagents.
Synthesis of benzanilide derivatives as dual acting agents with α1- adrenoceptor antagonistic action and steroid 5-α reductase inhibitory activity
Yoshida, Kiyoshi,Horikoshi, Yoichiro,Eta, Masaaki,Chikazawa, Jun,Ogishima, Masayuki,Fukuda, Yohichi,Sato, Hiroki
, p. 2967 - 2972 (2007/10/03)
Synthesis of benzanilide derivatives which have dual α1-adrenoceptor antagonistic action and steroid 5α-reductase inhibitory activity and their structure-activity relationships is described.
