219753-93-2

Upstream product

• 696-62-8 para-iodoanisole 
• 870-50-8 di-tert-butyl-diazodicarboxylate 
• 870-46-2 t-butoxycarbonylhydrazine 
• 5720-07-0 4-methoxyphenylboronic acid 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 16466-61-8 1,2-bis(t-butyloxycarbonyl)hydrazine 
• 623-12-1 4-chloromethoxybenzene 
• 24424-99-5 di-tert-butyl dicarbonate 
• 213596-33-9 2-(4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborolane 
• 870-50-8 di-tert-butyl (E)-azodicarboxylate 

Downstream Products

• 3471-32-7 4-Methoxyphenylhydrazine 

Relevant academic research and scientific papers

Amination of Arylboronic Compounds via the Copper-Catalyzed Addition of Arylboronic Esters to Azodicarboxylates

Arylboronic esters add to di-tert-butyl azodicarboxylate under mild reaction conditions (at room temperature) to afford aryl-substituted hydrazine derivatives in good yields. The reaction tolerates a wide variety of functional groups.

A Modular Approach to Arylazo-1,2,3-triazole Photoswitches

Azoheteroarenes make up an emerging class of photoswitchable compounds with unique photophysical properties and advantages over traditional azobenzenes. Therefore, methods for synthesizing azoheteroarenes are highly desirable. Here, we utilize azide-alkyne click chemistry to access arylazo-1,2,3-triazoles, a previously unexplored class of azoheteroarenes that exhibit high thermal stabilities and near-quantitative bidirectional photoconversion. Controlling the catalyst or 1,3-dipole grants access to both regioisomeric arylazotriazoles and arylazoisoxazoles, highlighting the versatility of our approach.

Cp?Rh(III)-catalyzed electrophilic amination of arylboronic acids with azo compounds for synthesis of arylhydrazides

A [Cp?Rh(iii)]-catalyzed electrophilic amination of arylboronic acids with diethyl azodicarboxylate (DEAD) was developed, and arylhydrazides were produced in excellent yields and selectivity. The analogous amination with the arylazocarboxylates afforded t

An efficient Pd-catalyzed coupling of hydrazine derivatives with aryl halides

A convenient method for the intermolecular N-arylation of hydrazides with aryl halides in the presence of a palladium catalyst, a MOP-type ligand, and Cs2CO3 is reported. The reaction gives coupling products in good to excellent yiel

Novel chromogenic substances and use thereof for the determination of carboxypeptidase activities

The invention relates to chromogenic compounds and the use thereof for the determination of enzymes of the family of carboxypeptidases N and carboxypeptidases U. The above is more specifically a compound of formula (I) in which A=(1), (2), (3), (4) or (5). R1. R2=H. —CH3, —CH(CH3)2, —OCH3, —Cl.—CF3,—OCF3,—SCH3, R3=an amino acid group which may be hydrolysed by a carboxypeptidase A and R4=a basic amino acid group.

Copper salt catalyzed addition of arylboronic acids to azodicarboxylates

The addition of arylboronic acids 1 to azodicarboxylates 2 in the presence of a catalytic amount of a copper salt under mild reaction conditions gives aryl-substituted hydrazines 3 in high yields. The reaction is tolerant of a wide variety of functional groups.

Synthesis of Diprotected Monosubstituted Hydrazine Derivatives from tert-Butyl Carbazates and Boronic Acids

(Equation presented) Diprotected monosubstituted hydrazine derivatives have been prepared via the reaction of tert-butyl carbazates with boronic acids catalyzed by cuprous chloride at room temperature.

Electrophilic amination of organozinc halides

The reaction of several functionalized primary, secondary and tertiary organozinc bromides, benzylzinc bromide, functionalized arylzinc halides and one heteroarylzinc bromide with ditert-butyl azodicarboxylate is described. The reaction products, N,N'-dit