219814-29-6

Basic information

• Product Name: 2,5-Dibromo-4-methylimidazole
• Synonyms: 2,5-DIBROMO-4-METHYLIMIDAZOLE;2,5-Dibromo-4-methyl-1H-imidazole;1H-Imidazole, 2,4-dibromo-5-methyl-
• CAS NO: 219814-29-6
• Molecular Formula: C₄H₄Br₂N₂
• Molecular Weight: 239.9
• Product Categories: blocks;Bromides;Imidazoles;Imidazol&Benzimidazole
• Mol File: 219814-29-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 343.104 °C at 760 mmHg
• Flash Point: 161.304 °C
• Appearance: /
• Density: 2.188 g/cm³
• Vapor Pressure: 7.2E-05mmHg at 25°C
• Refractive Index: 1.629
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 9.47±0.10(Predicted)
• CAS DataBase Reference: 2,5-Dibromo-4-methylimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dibromo-4-methylimidazole(219814-29-6)
• EPA Substance Registry System: 2,5-Dibromo-4-methylimidazole(219814-29-6)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 219814-29-6(Hazardous Substances Data)

Usage

General Description

2,5-Dibromo-4-methylimidazole is a chemical compound with the molecular formula C5H5Br2N. It is a derivative of imidazole, which is a five-membered ring with two nitrogen atoms. 2,5-Dibromo-4-methylimidazole is used in various industrial applications, including as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as a corrosion inhibitor in water treatment and as a biocide in the control of microbial growth in industrial processes. 2,5-Dibromo-4-methylimidazole is a white to off-white solid that is sparingly soluble in water but soluble in organic solvents, making it suitable for a wide range of applications. It should be handled with care due to its potential to cause irritation and harm if it comes into contact with skin or eyes.

InChI:InChI=1/C4H4Br2N2/c1-2-3(5)8-4(6)7-2/h1H3,(H,7,8)

Upstream product

• 822-36-6 4-methyl-1H-imidazole 
• 822-36-6 4-Methylimidazole 

Downstream Products

• 219814-20-7 1-(2-methyl-4-nitro-benezenesulphonyl)-2,4-dibromo-5-methyl-1H-imidazole 
• 23328-88-3 2-bromo-4-methyl-1H-imidazole 
• 822-36-6 4-methyl-1H-imidazole 
• 15813-08-8 5-bromo-4-methyl-1H-imidazole 
• 850429-57-1 2,4-dibromo-1,5-dimethyl-1H-imidazole 
• 850429-58-2 2,5-dibromo-1,4-dimethyl-1H-imidazole 

Relevant articles and documents

Efficient Synthesis of tert-Butyl 2,4-Dialkynylated and 2-Alkynylated-4-Arylated-1H-Imidazole-1-Carboxylate via Regioselective Sonogashira Cross-Coupling Reaction

An efficient regioselective cross-coupling reactions of tert-butyl 2,4-dibrominated-5-methyl-1H-imidazole-1-carboxylate is reported. This new synthetic route runs under simple and mild conditions and selectively gives an easy access to 2,4-dialkynylated a

Access to imidazo[1,2-a]imidazolin-2-ones and functionalization through Suzuki-Miyaura cross-coupling reactions

We report herein a synthetic pathway to new 6(5)-bromo-5(6)- methylimidazo[1,2-a]imidazolin-2-ones. The synthetic potential of these scaffolds was demonstrated by displacing bromine by Suzuki-Miyaura cross-coupling reactions. A large panel of boronic acids (aryl, heteroaryl or vinyl) could easily be introduced, giving access to a large and diversified library of 6(5)-substituted 5(6)-methylimidazo[1,2-a]imidazolin-2-ones. A new route to 6(5)-bromo-5(6)-methylimidazo[1,2-a]imidazolin-2-ones have been developed. A novel and effective strategy of functionnalization of these scaffolds throught Suzuki-Miyaura cross coupling reactions is reported. Thanks to this methodology, a large panel of boronic acids were easily introduced, giving access to a diversified library of 6(5)-substituted 5(6)-methylimidazo[1, 2-a]imidazolin-2-ones. Copyright