219838-90-1Relevant academic research and scientific papers
A fully integrated high-throughput screening methodology for the discovery of new polyolefin catalysts: Discovery of a new class of high temperature single-site group (IV) copolymerization catalysts
Boussie, Thomas R.,Diamond, Gary M.,Goh, Christopher,Hall, Keith A.,LaPointe, Anne M.,Leclerc, Margarete,Lund, Cheryl,Murphy, Vince,Shoemaker, James A. W.,Tracht, Ursula,Turner, Howard,Zhang, Jessica,Uno, Tetsuo,Rosen, Robert K.,Stevens, James C.
, p. 4306 - 4317 (2003)
For the first time, new catalysts for olefin polymerization have been discovered through the application of fully integrated high-throughput primary and secondary screening techniques supported by rapid polymer characterization methods. Microscale 1-octene primary screening polymerization experiments combining arrays of ligands with reactive metal complexes M(CH2Ph)4 (M = Zr, Hf) and multiple activation conditions represent a new high-throughput technique for discovering novel group (IV) polymerization catalysts. The primary screening methods described here have been validated using a commercially relevant polyolefin catalyst, and implemented rapidly to discover the new amide-ether based hafnium catalyst [η2- (N,O)-(2-MeO-C6H4) (2,4,6-Me3C6H2)N]Hf (CH2Ph)3 (1), which is capable of polymerizing 1-octene to high conversion. The molecular structure of 1 has been determined by X-ray diffraction. Larger scale secondary screening experiments performed on a focused 96-member amine-ether library demonstrated the versatile high temperature ethylene-1-octene copolymerization capabilities of this catalyst class, and led to significant performance improvements over the initial primary screening discovery. Conventional one gallon batch reactor copolymerizations performed using selected amide-ether hafnium compounds confirmed the performance features of this new catalyst class, serving to fully validate the experimental results from the high-throughput approaches described herein.
