219865-79-9 Usage
General Description
2-METHYL-6-[(2,2,2-TRIFLUOROACETYL)AMINO]BENZOIC ACID is a chemical compound with the molecular formula C10H9F3NO3. It is a derivative of benzoic acid with a trifluoroacetyl group and an amino group attached to the 6th position of the benzene ring. 2-METHYL-6-[(2,2,2-TRIFLUOROACETYL)AMINO]BENZOIC ACID is often used as a building block in organic synthesis and medicinal chemistry. Its unique structure and functional groups make it valuable for the development of pharmaceuticals, agrochemicals, and other specialty chemicals. It is also used as a research chemical in various scientific studies.
Check Digit Verification of cas no
The CAS Registry Mumber 219865-79-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,8,6 and 5 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 219865-79:
(8*2)+(7*1)+(6*9)+(5*8)+(4*6)+(3*5)+(2*7)+(1*9)=179
179 % 10 = 9
So 219865-79-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H8F3NO3/c1-5-3-2-4-6(7(5)8(15)16)14-9(17)10(11,12)13/h2-4H,1H3,(H,14,17)(H,15,16)
219865-79-9Relevant articles and documents
The design and synthesis of novel orally active inhibitors of AP-1 and NF-κB mediated transcriptional activation. SAR of in vitro and in vivo studies
Palanki, Moorthy S. S.,Erdman, Paul E.,Ren, Minghuan,Suto, Mark,Bennett, Brydon L.,Manning, Anthony,Ransone, Lynn,Spooner, Cheryl,Desai, Sonal,Ow, Arnie,Totsuka, Ryuichi,Tsao, Peter,Toriumi, Wataru
, p. 4077 - 4080 (2007/10/03)
We have developed novel orally active quinazoline analogues as inhibitors of AP-1 and NF-κB mediated transcriptional activation. Among the derivatives prepared, 1-[2-(2-thienyl)quinazolin-4-ylamino]-3-methyl-3- pyrroline-2,5-dione (10) showed significant activity in an adjuvant-induced arthritis rat model by reducing the swelling by 65% in the non-injected foot. The synthesis, structure-activity relationship, and in vivo activity are described.
Xi:Irritant;
