21987-14-4Relevant academic research and scientific papers
Synthesis of a glycolipid for studying mechanisms of mitochondrial uncoupling proteins
Gouin, Sebastien G.,Pilgrim, Wayne,Porter, Richard K.,Murphy, Paul V.
, p. 1547 - 1552 (2007/10/03)
Glucose-O-ω-palmitic acid is an amphipathic molecule that is useful as a tool for studying the mechanism of mitochondrial uncoupling proteins. The synthesis of this glycolipid is described herein. The study of the reaction of a series of glycosyl donors with appropriate acceptors derived from 16-hydroxyhexadecanoic acid showed that a glycosyl trichloroacetimidate donor was more efficient than thioglycoside, glycosyl halide and glycosyl acetate donors for synthesis of this glycolipid.
