2199-85-1

Basic information

• Product Name: 3-Benzoyl-6-broMochroMen-2-one
• Synonyms: 3-Benzoyl-6-broMochroMen-2-one;3-benzoyl-6-broMo-2H-chroMen-2-one
• CAS NO: 2199-85-1
• Molecular Formula: C₁₆H₉BrO₃
• Molecular Weight: 329.14486
• Mol File: 2199-85-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Benzoyl-6-broMochroMen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Benzoyl-6-broMochroMen-2-one(2199-85-1)
• EPA Substance Registry System: 3-Benzoyl-6-broMochroMen-2-one(2199-85-1)

Safety Data

• Hazardous Substances Data: 2199-85-1(Hazardous Substances Data)

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 1761-61-1 5-bromosalicyclaldehyde 
• 19063-55-9 6-bromo-2H-chromen-2-one 
• 1074-12-0 phenylglyoxal hydrate 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 

Downstream Products

• 1615724-62-3 3-benzoyl-6-bromo-4-(5-methylthiophen-2-yl)-2H-chromen-2-one 

Relevant articles and documents

Enantioselective synthesis of coumarin derivatives catalyzed by primary amines

Cinchona alkaloid-derived primary amines were used as organocatalysts for the preparation of enantioenriched coumarin derivatives. A series of optically active coumarin derivatives was obtained in good yields with excellent enantioselectivities (up to 98%

Design, synthesis and antibacterial study of new potent and selective coumarin-chalcone derivatives for the treatment of tenacibaculosis

With the aim of finding new chemical entities selective for fish pathogens to avoid drug resistance in humans, a series of coumarin-chalcone hybrid compounds with different patterns of substitution were designed and synthesized. Their antibacterial activi

Dual Role of Oxoaldehydes: Divergent Synthesis of 3-Aryl- and 3-Aroylcoumarins

A facile and efficient synthetic approach to various valuable 3-aryl- and 3-aroylcoumarins by the direct arylation and aroylation of coumarins with glyoxals in a metal-free manner is presented. The aryl glyoxal is for the first time recognized to serve as an aryl surrogate in addition to its role as an aroyl transfer reagent via a simple switch in reaction conditions. The approach accommodates a broad substrate scope and high yields of the two types of cross-coupling reactions starting from identical starting materials.

An efficient synthesis of some new coumarin hybrids endowed with expected biological activity

Reactions of 5-bromo-2-hydroxybenzaldehyde with cyanoacetic acid hydrazide derivatives in refluxing ethanol afforded some new chromene-based polyfunctionally substituted heteroaromatics. The antimicrobial activity of some of the obtained products was eval

Palladium-Catalyzed Carbonylation of Coumarin C(sp 2)-H Bonds: A New Entry to Arylcoumarin Ketones

A facile and efficient palladium-catalyzed carbonylation of coumarins involving two C-C bond formations has been developed. The C-H bond oxidative functionalization proceeds through aroylation with insertion of carbon monoxide to give arylcoumarin ketones

The synthesis of coumarin derivatives using choline chloride/zinc chloride as a deep eutectic solvent

In this work, choline chloride/zinc chloride was employed as a deep eutectic solvent (DES) in the green synthesis of coumarin derivatives using Knoevenagel condensation. Coumarins are important organic structures with useful application in various fields.

The indium(iii) chloride catalyzed synthesis of sulfur incorporated 3-acylcoumarins; Their photochromic and acetate sensing properties

The synthesis and evaluation of the photochromic properties of 3-acylcoumarins are very important as they exhibit selective sensing properties. We found that InCl3 efficiently catalyzes the condensation of 2-hydroxybenzaldehydes and β-keto este

Synthesis of 3-Substituted coumarins: An efficient green approach using l-Proline as catalyst in triethanolamine medium

3-Substituted coumarins were synthesized very efficiently, using Knoevenagel method from salicylaldehydes 1 and active methylene compounds 2 under green conditions. The effect of catalyst and solvent on this condensation was studied. L-Proline was found t

DABCO and Bu3P catalyzed [4 + 2] and [3 + 2] cycloadditions of 3-acyl-2H-chromen-ones and ethyl 2,3-butadienoate

DABCO-catalyzed [4 + 2] and Bu3P-catalyzed [3 + 2] cycloadditions between 3-acyl-2H-chromen-ones and ethyl 2,3-butadienoate were developed for the synthesis of dihydropyran-fused and cyclopenten-fused chromen-2-ones with high regio- and stereo-

Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions

A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylpho