219921-93-4

Basic information

• Product Name: (R)-3-methyl-1-(2-(1-pieridinyl)phenyl)-butylamine
• Synonyms: (R)-3-methyl-1-(2-(1-pieridinyl)phenyl)-butylamine
• CAS NO: 219921-93-4
• Molecular Weight: 246.396
• Mol File: 219921-93-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-3-methyl-1-(2-(1-pieridinyl)phenyl)-butylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-methyl-1-(2-(1-pieridinyl)phenyl)-butylamine(219921-93-4)
• EPA Substance Registry System: (R)-3-methyl-1-(2-(1-pieridinyl)phenyl)-butylamine(219921-93-4)

Safety Data

• Hazardous Substances Data: 219921-93-4(Hazardous Substances Data)

Usage

General Description

(R)-3-methyl-1-(2-(1-pieridinyl)phenyl)-butylamine is a chemical compound with the molecular formula C18H25N. It is an amine compound with a butylamine chain and a phenyl group containing a pyridine ring. The compound is chiral, with the (R) enantiomer being the active form. It is used in the synthesis of pharmaceuticals and other organic compounds. It may also have biological activity and potential applications in drug development and research.

Upstream product

• 34595-26-1 2-(piperidin-1-yl)benzaldehyde 
• 590-86-3 isovaleraldehyde 
• 82212-00-8 1-(2-bromophenyl)piperidine 
• 1026508-90-6 [3-Methyl-1-(2-piperidin-1-yl-phenyl)-but-3-enyl]-[1-(2-piperidin-1-yl-phenyl)-meth-(E)-ylidene]-amine 
• 219921-97-8 N-<(R)-3-methyl-1-<2-(1-piperidinyl)phenyl>butyl>-N-<(R')-1-phenethyl>-amine 
• 147770-01-2 N-<(S)-3-methyl-1-<2-(1-pieridinyl)phenyl>butyl>-N-<(S')-1-phenethyl>-amine 
• 219922-07-3 N-<(S)-3-methyl-1-<2-(1-piperidinyl)phenyl>butyl>-N-<(R')-1-phenethyl>-amine 
• 147769-97-9 N-acetyl-N-<3-methyl-1-(2-(1-piperidinyl)phenyl)-1-(Z)-buten-1-yl>-amine 
• 147769-96-8 3-methyl-1-[2-(piperidin-1-yl)phenyl]butan-1-imine 
• 147769-93-5 (1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butan-1-amine 
• 147770-03-4 3-methyl-1-(2-piperidin-1-yl-phenyl)-butan-1-one 
• 873-32-5 2-Chlorobenzonitrile 
• 72752-52-4 2-(piperidin-1-yl)benzonitrile 
• 110-89-4 piperidine 

Downstream Products

• 147770-08-9 (R)-(-)-ethyl 2-ethoxy-4-<2-<<3-methyl-1-<2-(1-piperidinyl)phenyl>butyl>amino>-2-oxoethyl>-benzoate 
• 1334218-78-8 S-PPA*3,5-DNTA 
• 1334218-79-9 S-PPA*3,5-DNBA 
• 1334218-75-5 rac-PPA*3,5-DNTA 
• 108157-52-4 (S)-1-(2-piperidino-phenyl)-3-methyl-1-butylamine 

Relevant articles and documents

Reversal diastereoselectivity between the organomagnesium and organolithium reagents on Chiral N-tert-butylsulfinylaldimines for the preparation of chiral amines

The asymmetric synthesis of both the enantiomer of chiral amines from the single chiral source of N-tert-butylsulfinylaldimines (3) by simply changing the organometallic reagents through diastereoselective addition. An efficient enantioselective synthesis of chiral amines including (S)-3-methyl-1-(2- piperidin-1-yl-phenyl)butyl amine (6a), a key intermediate to prepare antidiabetic drug repaglinide (1), is reported.

Process for the preparation of substantially optically pure Repaglinide and precursors thereof

The invention relates to a process for preparing substantially optically pure Repaglinide and pharmaceutically acceptable salts, solvates and esters thereof, as well as precursors therefore.