219924-00-2Relevant academic research and scientific papers
Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatology
Meerpoel, Lieven,Backx, Leo J. J.,Van Der Veken, Louis J. E.,Heeres, Jan,Corens, David,De Grout, Alex,Odds, Frank C.,Van Gerven, Frans,Woestenborghs, Filip A. A.,Van Breda, Andre,Oris, Michel,Van Dorsselaer, Pascal,Willemsens, Gustaaf H. M.,Vermuyten, Karen J. P.,Marichal, Patrick J. M. G.,Vanden Bossche, Hugo F.,Ausma, Jannie,Borgers, Marcel
, p. 2184 - 2193 (2007/10/03)
In search for new compounds with potential for clinical use as antifungal agents in dermatology, a series of 12 azole compounds were synthesized stereospecifically and investigated specifically for their activity against dermatophyte fungal infections in
2,4,4-trisubstituted-1,3-dioxolane antifungals
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, (2008/06/13)
The present invention concerns novel compounds of formula a N-oxide form, a pharmaceutically acceptable acid addition salt or a stereochemically isomeric form thereof, wherein n is zero, 1, 2 or 3; X is N or CH; each R1independently is halo, ni
