219926-41-7

Usage

Structure

A derivative of benzene with two bromine atoms and two fluorine atoms attached to different carbon atoms in the benzene ring.

Usage

Primarily used in organic synthesis.

Applications

Commonly employed in the production of pharmaceuticals, agrochemicals, and other specialty chemicals.

Additional uses

Used as an intermediate in the manufacture of dyes, perfumes, and other aromatic compounds.

Physical state

Colorless to light yellow liquid at room temperature.

Toxicity

Moderately toxic.

Safety

Should be handled with caution and in accordance with proper safety protocols.

Upstream product

• 64248-56-2 1-bromo-2,6-difluorobenzene 
• 219926-39-3 3-Bromo-2,6-difluorophenyltrimethylsilane 
• 348-57-2 2,4-difluorobromobenzene 
• 148854-10-8 (2,4-difluorophenyl)trimethylsilane 

Downstream Products

• 1184298-51-8 2,6-difluoro-3-(2-oxo-pyrrolidinyl)-benzenesulfonyl chloride 
• 1184298-50-7 1-(3-benzylsulfanyl-2,4-difluoro-phenyl)-pyrrolidin-2-one 
• 1184298-48-3 5-chloro-thiophene-2-carboxylic acid [(S)-2-[2,6-difluoro-3-(2-oxo-pyrrolidin-1-yl)-benzenesulfonylamino]-3-(4-methyl-piperazin-1-yl)-3-oxo-propyl]-amide hydrochloride 

Relevant academic research and scientific papers

Metal complex containing phenyl-pyridines connected to carbazoles, it's preparation method and it's applications

PURPOSE: A carbazole structure-connected phenyl-pyridien metal complex compound is provided to use in a blue organic light emitting diode. CONSTITUTION: A metal complex compound contains a phernylpyridine structure which is connected with carbazole structure of chemical formula 1. In chemical formula 1, M is a metal having 40 or more of atomic weight; m is 1 or more; n is 0 or more; X-Y is ancillary ligand; and R1 is alkyl of C1-16 or alkyl ether group of C1-16. A light emitting device contains an organic layer having a compound of phenyl-pyridine structure.

Electrophilic ipso substitution of trimethylsilyl groups in fluorobenzenes

Using variants of literature methods 2,4- and 2,6- difluorophenyltrimethylsilanes have been bromodesilylated to the corresponding bromodifluorobenzenes in moderate to good yields, 3-bromo-2,6-difluorophenyltrimethylsilane afforded 1,3-dibromo-2,4-difluorobenzene whilst 1,3-difluoro-2,4-bis(trimethylsilyl)benzene yielded 3-bromo-2,6-difluorophenyltrimethylsilane. Application of either the Eaborn or Chvalovsky methods of nitrodesilylation to 4-fluorophenyltrimethylsilane, 2,4-difluorophenyltrimethylsilane and 2,6-difluorophenyltrimethylsilane afforded largely the corresponding desilylated products together with products associated with initial protodesilylation, followed by nitration of the resulting fluorobenzenes. The results obtained show that ipso desilylation in the fluoroaromatic series does follow the expected pattern previously obtained in the hydrocarbon analogues. They also show that in some cases the formation of unusually substituted fluoroarenes can be achieved more readily than by the methods previously used.