219926-64-4

Upstream product

• 80532-35-0 (2Z)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-en-1-ol 
• 91926-90-8 ethyl (Z)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 

Downstream Products

• 613682-70-5 (+)-(2S,3Z)-5-benzenesulfonyl-pent-3-ene-1,2-diol 
• 613682-76-1 (+)-2-[2-benzenesulfonyl-1-(2-methoxymethoxy-cyclopropyl)-ethyl]-5-isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazine 
• 613682-71-6 (+)-(2S,3Z)-5-benzenesulfonyl-1-tosyloxy-pent-3-en-2-ol 
• 613682-73-8 (-)-(2S,3Z)-5-benzenesulfonyl-1-iodo-2-(tetrahydropyran-2-yloxy)-pent-3-ene 
• 613682-74-9 (-)-(2S,3Z)-5-benzenesulfonyl-1-iodo-2-tert-butyldimethylsilyloxy-pent-3-ene 
• 613682-75-0 (-)-(2S,3Z)-5-benzenesulfonyl-1-iodo-2-methoxymethoxy-pent-3-ene 
• 613682-72-7 (+)-(2S,3Z)-5-benzenesulfonyl-1-iodo-pent-3-en-2-ol 
• 527729-63-1 (-)-(1R,2R)-2-(2-benzenesulfonylvinyl)-1-tert-butyldimethylsililoxy-cyclopropane 
• 527729-51-7 (-)-(1R,2S)-2-(2-benzenesulfonylvinyl)-1-tert-butyldimethylsililoxy-cyclopropane 
• 527729-58-4 (+)-(1R,2R)-2-(2-benzenesulfonylvinyl)-1-methoxymethoxy-cyclopropane 
• 527729-45-9 (-)-(1R,2S)-2-(2-benzenesulfonylvinyl)-1-methoxymethoxy-cyclopropane 
• 435286-54-7 (-)-(1R,2R)-2-[2-(2-benzenesulfonylvinyl)-1-(tetrahydropyran-2-yloxy)]-cyclopropane 
• 435286-51-4 (+)-(1R,2S)-2-[2-(2-benzenesulfonylvinyl)-1-(tetrahydropyran-2-yloxy)]-cyclopropane 
• 219926-67-7 (2E,4E)-5-Phenylsulfonylpenta-2,4-dien-1-ol 

Relevant academic research and scientific papers

Stereoselective synthesis of 1-hydroxymethyl-4-phenylsulfonylbutadienes

Stereoselective syntheses of 1-hydroxymethyl-4-phenylsulfonylbutadienes were achieved from unsaturated sulfones which were easily obtained from D-Mannitol.

On The Stereoselectivity the Synthesis of 1-Hydroxymethyl-4-phenylsulfonylbuta-1,3-dienes from β,γ-Unsaturated Sulfones

Starting from D-mannitol, eight β,γ-unsaturated sulfones with different substitution patterns have been synthesised. Reaction of these sulfones with different bases led to 1-hydroxymethyl-4-phenylsulfonylbuta-1,3-dienes with excellent stereocontrol. The stereoselectivity of this reaction is explained and an abbreviated reaction course is proposed that justifies the results obtained.