21993-16-8Relevant academic research and scientific papers
Novel approach to the synthesis of alkoxycarbonylmethyl- and bis(alkoxycarbonylmethyl)phosphine oxides based on a Reformatsky-type reaction
Kielbasinski,Mikolajczyk
, p. 144 - 146 (1995)
A new procedure for the preparation of alkoxycarbonylmethyl- and bis(alkoxycarbonylmethyl)phosphine oxides is described, which consists of a Reformatsky-type reaction between chlorophosphines or dichlorophosphines and alkyl bromoacetates in the presence o
Copper-Catalyzed Decarboxylative Hydrophosphinylation of α-Acyl-α-Diazoacetates
Zhang, Can,Dong, Chao,Wang, Xin,Shen, Ruwei
supporting information, p. 7440 - 7444 (2020/12/01)
A simple copper-catalyzed decarboxylation–denitrogenation C–P coupling reaction of α-acyl-α-diazoacetates with hydrophosphoryl compounds is reported. The reaction may proceed via a process involving the generation of (diazomethyl)ketones after hydrolysis in the presence of water and the hydrophosphinylation of the copper carbene intermediates. This finding may suggest the potential use of the relatively more readily available α-acyl-α-diazoacetates as replacement of (diazomethyl)ketones in some cases.
ALKYLATION REACTIONS OF DIALKYL HYDROGEN PHOSPHITES AND DIARYLPHOSPHINE OXIDES UNDER PHASE-TRANSFER CONDITIONS
Petrov, K. A.,Sivova, L. I.,Smirnov, I. V.,Kryukova, L. Yu.
, p. 264 - 268 (2007/10/02)
It was shown that phosphonates and tertiary phosphine oxides can be synthesized by the alkylation of acid phosphites and diarylphosphine oxides in a nonpolar solvent in presence of solid potassium hydroxide and potassium carbonate and also catalytic amounts of 18-crown ether (or in its absence). (Diarylphosphinyl)methyl ethers of mono- and oligo-etylene glycols were synthesized by the reactions of diaryl(chloromethyl)phosphine oxides with lithium glycolates
