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N-SUCCINIMIDOXYCARBONYL-?-ALANINE N-SUCCINIMIDYL ESTER,1,4DIOXANE COMPLEX is a short, amino reactive homobifunctional crosslinking reagent. It is soluble in 1,4-dioxane and can be used for polymer coupling to proteins. This reagent is particularly useful for creating PEG-protein conjugates with better selectivity among the amino groups present in a protein, resulting in less heterogeneous mixtures.

21994-89-8

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21994-89-8 Usage

Uses

Used in Pharmaceutical Industry:
N-SUCCINIMIDOXYCARBONYL-?-ALANINE N-SUCCINIMIDYL ESTER,1,4DIOXANE COMPLEX is used as a crosslinking reagent for the development of PEG-protein conjugates. It is particularly useful for improving the selectivity among the amino groups present in a protein, leading to the formation of less heterogeneous PEG-protein conjugates. This results in more efficient and targeted drug delivery systems.
Used in Research and Development:
In research and development, N-SUCCINIMIDOXYCARBONYL-?-ALANINE N-SUCCINIMIDYL ESTER,1,4DIOXANE COMPLEX is used as a homobifunctional crosslinking reagent for studying protein-protein interactions and the effects of PEGylation on protein stability and function. The reagent's selectivity for the most nucleophilic and solvent-exposed amines allows for more controlled and specific conjugation, facilitating a better understanding of protein behavior and potential applications.

Check Digit Verification of cas no

The CAS Registry Mumber 21994-89-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,9 and 4 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 21994-89:
(7*2)+(6*1)+(5*9)+(4*9)+(3*4)+(2*8)+(1*9)=138
138 % 10 = 8
So 21994-89-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N3O8.C4H8O2/c16-7-1-2-8(17)14(7)22-11(20)5-6-13-12(21)23-15-9(18)3-4-10(15)19;1-2-6-4-3-5-1/h1-6H2,(H,13,21);1-4H2

21994-89-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-Succinimidoxycarbonyl-?-alanine N-Succinimidyl Ester 1,4- Dioxane complex

1.2 Other means of identification

Product number -
Other names b-Alanine,N-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-,2,5-dioxo-1-pyrrolidinyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21994-89-8 SDS

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