21997-23-9 Usage
Uses
Used in Pharmaceutical Industry:
5-Nitro-1-benzofuran-2(3H)-one is used as a key intermediate in the synthesis of various drugs for its antimicrobial and anti-inflammatory properties. It serves as a fundamental component in the creation of medications designed to combat bacterial and fungal infections, as well as to alleviate inflammation.
Used in Research and Development:
In the scientific community, 5-Nitro-1-benzofuran-2(3H)-one is utilized in research for exploring its potential applications in treating a range of diseases and conditions. Its pharmacological properties are under investigation to understand its full therapeutic potential and to develop new therapeutic agents.
Used in Drug Discovery:
5-Nitro-1-benzofuran-2(3H)-one is employed as a starting material in drug discovery processes, where its chemical structure can be modified to create new compounds with specific therapeutic effects. This makes it a versatile tool in medicinal chemistry for the development of novel pharmaceuticals.
Used in Organic Synthesis:
Beyond its pharmaceutical applications, 5-Nitro-1-benzofuran-2(3H)-one is also used in organic synthesis for the preparation of other organic compounds. Its unique structure allows for various chemical reactions, making it a useful precursor in the synthesis of a wide array of organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 21997-23-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,9 and 7 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21997-23:
(7*2)+(6*1)+(5*9)+(4*9)+(3*7)+(2*2)+(1*3)=129
129 % 10 = 9
So 21997-23-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H5NO4/c10-8-4-5-3-6(9(11)12)1-2-7(5)13-8/h1-3H,4H2
21997-23-9Relevant academic research and scientific papers
Phosphine-Catalyzed Domino β/γ-Additions of Benzofuranones with Allenoates: A Method for Unsymmetrical 3,3-Disubstituted Benzofuranones
Huang, Zhusheng,Yang, Xiuqin,Yang, Fulai,Lu, Tao,Zhou, Qingfa
supporting information, p. 3524 - 3527 (2017/07/17)
A phosphine-catalyzed domino process of benzofuranones with allenoates has been developed which furnishes highly functionalized unsymmetrical 3,3-disubstituted benzofuranones in synthetically useful yields. The mechanism for the transformation is a tandem β-umpolung/γ-umpolung process.
