553-86-6Relevant articles and documents
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Ghose et al.
, p. 95 (1954)
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Baciocchi et al.
, p. 32 (1979)
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Pd(II)-catalyzed ortho -C-H oxidation of arylacetic acid derivatives: Synthesis of benzofuranones
Rit, Raja K.,Yadav, M. Ramu,Sahoo, Akhila K.
, p. 968 - 971 (2014)
Pd(II)-catalyzed ortho-C-H acetoxylation of arylacetic acid derivatives is demonstrated with the aid of a novel S-methyl-S-2-pyridylsulfoximine (MPyS) directing group (DG). The α-mono- and α-unsubstituted arylacetic acid derivatives were readily employed in the ortho-C-H acetoxylations. The oxidation products are hydrolyzed, and the MPyS-DG is easily recovered, providing ready access to o-hydroxyarylacetic acids. 3-Mono- and 3-unsubstituted benzofuranones are synthesized from o-hydroxyarylacetic acids.
Regioselective Synthesis of Benzofuranones and Benzofurans
Zhang, Xiaojie,Beaudry, Christopher M.
supporting information, p. 6931 - 6936 (2021/05/06)
Reaction of 3-hydroxy-2-pyrones with nitroalkenes bearing ester groups gives benzofuranones. The reaction allows regioselective preparation of the benzofuranones with programmable substitution at any position. Complex substitution patterns are readily cre
Synthetic method of benzofuranone
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Page/Page column 8-10, (2020/06/16)
The invention provides a synthetic method of benzofuranone. According to the method, o-cresol which is relatively easy to obtain is used as an initial raw material, and the target product benzofuranone is prepared through four-step reaction; and the whole preparation process is mild in condition, high in yield, easy to operate, small in environmental pollution and suitable for large-scale industrial production.