219992-25-3Relevant academic research and scientific papers
Hydrogen bonding and attenuation of the rate of enzymic catalysis
Li, Zhi-Hong,Bulychev, Alexey,Kotra, Lakshmi P.,Massova, Irina,Mobashery, Shahriar
, p. 13003 - 13007 (1998)
Hydrogen bonds between a small molecule and an enzyme can potentially contribute significantly to the stability of the complex. Such electrostatic interactions can also lower energy barriers for reactions by solvation of high-energy species. A novel type
