2201-10-7

Basic information

• Product Name: Benzene, 1-methyl-4-(2,2,2-trichloroethyl)-
• CAS NO: 2201-10-7
• Molecular Formula: C9H9Cl3
• Molecular Weight: 223.529
• Mol File: 2201-10-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-4-(2,2,2-trichloroethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-4-(2,2,2-trichloroethyl)-(2201-10-7)
• EPA Substance Registry System: Benzene, 1-methyl-4-(2,2,2-trichloroethyl)-(2201-10-7)

Safety Data

• Hazardous Substances Data: 2201-10-7(Hazardous Substances Data)

Upstream product

• 75-62-7 Bromotrichloromethane 
• 36583-14-9 para-methylbenzylbis(dimethylglyoximato)(pyridine)cobalt(III) 
• 75-35-4 1,1-Dichloroethylene 
• 2028-84-4 p-methylbenzenediazonium chloride 
• 106-49-0 p-toluidine 
• 80156-17-8 1-methylene-4-methyl-4-trichloromethyl-2,5-cyclohexadiene 
• 343855-23-2 1,4-dimethyl-4-trichloromethyl-2,5-cyclohexadien-1-ol 

Downstream Products

• 622-47-9 4-tolylacetic acid 
• 1227741-44-7 1-(4-fluorophenyl)-3-(p-tolyl)prop-2-yn-1-ol 
• 1227741-43-6 C₁₈H₁₆O₃ 
• 100-21-0 terephthalic acid 
• 50562-01-1 1-methyl-4-(2,2,2-trifluoroethyl)benzene 
• 114980-32-4 1-(2-Chloro-2,2-difluoro-ethyl)-4-methyl-benzene 
• 140654-53-1 1-(2,2-Dichloro-2-thiocyanato-ethyl)-4-methyl-benzene 

Relevant articles and documents

A phenylacetic acid compound preparation method (by machine translation)

The invention relates to the field of chemical synthesis, in particular relates to a preparation method of the compound of phenylacetic acid. The present invention provides a preparation method of the compound of phenylacetic acid, the acid compounds of the structural formula states the benzene second grade shown in formula I, the preparation method comprises the following steps: (1) diazo addition reaction: formula II compound containing vinylidene chloride, acid, diazotization reagent, phase transfer catalyst and a copper catalyst in the system of the formula III compound: (2) hydrolysis reaction: the compound of formula III in the presence of acid hydrolysis of formula I compounds. The present invention provides a preparation method of and is simple, easy operation, low cost of raw materials, mild reaction conditions, low risk, does not need to use expensive noble metal catalyst and complex industrial operation means, the product quality is stable, therefore easy achievement of large-scale industrial production. (by machine translation)

HOMOLYTIC DISPLACEMENT AT CARBON VI. SYNTHESIS OF TRICHLOROETHYLARENES FROM BENZYLCOBALOXIMES

Benzylbis(dimethylglyoximato)pyridinecobalt(III) reacts with bromotrichloromethane at from 50 to 90 deg C in chloroform to give good yields of trichloroethylbenzene, which are higher when imidazole is present in the reaction mixture.Methyl- and polymethyl-substituted benzylbis(dimethylglyximato)pyridinecobalt(III) complexes give higher yields of the corresponding trichloroethylarenes (85-90percent), whereas 4-chlorobenzylbis(dimethylglyoximato)pyridinecobalt(III) only gives the 4-nitro-trichloroethylarene when imidazole is present during the reaciton.Similar reactions were observed with benzylcobaloximes and trichloromethanesulphonyl chloride both thermally and under irradiation by tungsten lamps through all-pyrex apparatus.The reactions are interpreted as a direct attack of the trichloromethyl radical on the α-carbon of the benzyl ligand.