F+:Extremely flammable;
75-35-4Relevant academic research and scientific papers
Catalytic Dehydrochlorination of 1,1,2-Trichloroethane (TCE) into 1,1-Dichloroethene (DCE) over Cesium Nitrate Supported on Silica Gel
Mochida, Isao,Yasumoto, Yoshinori,Fujitsu, Hiroshi,Kojima, Yasuhiro
, p. 461 - 464 (1992)
Catalytic activity of silica gel-supported cesium salts was examined for the dehydrochlorination of TCE into DCE by recovering hydrogen chloride.Among the salts, CsNO3 showed the best activity, although it was converted into CsCl during the reaction.High dispersion of CsNO3 on silica gel may be a major reason of the high activity.
HIGH CATALYTIC ACTIVITY OF CsCl SUPPORTED ON SILICA GEL FOR THE SELECTIVE DEHYDROCHLORINATION OF 1,1,2-TRICHLOROETHANE
Mochida, Isao,Miyazaki, Tatsuro,Takagi, Takeshi,Fujitsu, Hiroshi
, p. 833 - 836 (1985)
CsCl supported on a particular silica gel dryed at 120 deg C, exhibited a remarkable activity fot selective dehydrochlorination of TCE into 1,1-DCE after the calcination around 500 deg C.The proper heat-treatment before and after impregnation of CsCl on the silica gel strongly influenced the activity of the catalyst.
Interaction and Catalytic Decomposition of 1,1,1-Trichloroethane on High Surface Area Alumina. An Infrared Spectroscopic Study
Ballinger, Todd H.,Yates, John T.
, p. 1417 - 1423 (1992)
Transmission infrared spectroscopy has been used to study the catalytic decomposition of 1,1,1-trichloroethane, CH3CCl3, on high surface area alumina, Al2O3, in the temperature range 300 - 600 K.At 300K CH3CCl3 is reversibly adsorbed on the isolated surface hydroxyl groups of Al2O3 via hydrogen bonding.At T >/= 400 K an α,β-HCl elimination occurs, forming CH2=CCl2(g).A small amount of surface carboxylate was also formed by means of a minor reaction pathway.It was found that Lewis acid (Al3+) surface sites were involved in causing the primary reaction.This was shown by the observation that irreversible adsorption of pyridine on the Al3+ sites efficiently quenched the surface reaction.Conversely, surface Al-OH groups are not involved in the CH3CCl3 decomposition.
Mesoporous carbon nitride as a basic catalyst in dehydrochlorination of 1,1,2-trichloroethane into 1,1-dichloroethene
Tian, Cong,Lu, Chunshan,Wang, Bolin,Xie, Xiangzhou,Miao, Yangsen,Li, Xiaonian
, p. 103829 - 103833 (2015)
1,1-Dichloroethene has many applications in industrial production and it holds great promise in developing a vapor phase catalytic dehydrochlorination process. We synthesized a carbon nitride material by dissolving dicyandiamide in N,N-dimethylformamide (DMF) as a precursor and using SBA-15 as a template. A carbon nitride material with a mesoporous structure and textured pores has been obtained and then characterized by N2-adsorption measurements, XRD, HRTEM, EDS and FT-IR. A mesoporous carbon nitride material with a surface area of 350 m2 g-1 and pore volume of 0.72 cm3 g-1 was fabricated, which also possessed triazine N heterocycles with extra amino groups. It is an outstanding heterogeneous base catalyst in the selective catalytic dehydrochlorination of 1,1,2-trichloroethane into 1,1-dichloroethene reaction with a maximum 1,1,2-trichloroethane conversion of 23.96% and maximum 1,1-dichloroethene selectivity of 100%. A total of 110 h stability experiment of the catalyst was provided and the selectivity stayed above 99% all through the experiment and the conversion remained no less than 15% for 35 h.
Method for eliminating hydrogen chloride by catalytic cracking of chloralkane
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Paragraph 0095-0100, (2020/08/06)
The invention discloses a method for eliminating hydrogen chloride by catalytic cracking of chloralkane, comprising the following steps of: carrying out a cracking reaction on chloralkane under the action of a biomass-based nitrogen-doped carbon catalyst to eliminate hydrogen chloride so as to prepare corresponding olefin, wherein the biomass-based nitrogen-doped carbon catalyst is prepared by carbonizing biomass or a mixture of biomass and a nitrogen source at 400-1000 DEG C, and the biomass is selected from at least one of bamboo processing leftovers, wood processing leftovers, plant straws,plant leaves, cereals, beans, cereal processing leftovers, bean processing leftovers and livestock manure. The method disclosed by the invention has the advantages of simple preparation process, easily available raw materials, low cost, strong process controllability, easiness in large-scale production, high catalytic cracking conversion rate of the chloralkane, high product selectivity, low energy consumption and the like.
Nitrogen-Doped Carbon-Assisted One-pot Tandem Reaction for Vinyl Chloride Production via Ethylene Oxychlorination
Chen, De,Chen, Qingjun,Fuglerud, Terje,Ma, Guoyan,Ma, Hongfei,Qi, Yanying,Rout, Kumar R.,Wang, Yalan
supporting information, p. 22080 - 22085 (2020/10/02)
A bifunctional catalyst comprising CuCl2/Al2O3 and nitrogen-doped carbon was developed for an efficient one-pot ethylene oxychlorination process to produce vinyl chloride monomer (VCM) up to 76 % yield at 250 °C and under ambient pressure, which is higher than the conventional industrial two-step process (≈50 %) in a single pass. In the second bed, active sites containing N-functional groups on the metal-free N-doped carbon catalyzed both ethylene oxychlorination and ethylene dichloride (EDC) dehydrochlorination under the mild conditions. Benefitting from the bifunctionality of the N-doped carbon, VCM formation was intensified by the surface Cl*-looping of EDC dehydrochlorination and ethylene oxychlorination. Both reactions were enhanced by in situ consumption of surface Cl* by oxychlorination, in which Cl* was generated by EDC dehydrochlorination. This work offers a promising alternative pathway to VCM production via ethylene oxychlorination at mild conditions through a single pass reactor.
METHOD OF PRODUCING VINYL CHLORIDE
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Paragraph 0031; 0038; 0039, (2020/01/27)
A method of producing vinyl chloride is provided in the present invention. The method includes the following steps. First, 1,2-dichloroethane (EDC) is introduced into a reactor, and a residence time of the EDC in an ionic liquid catalyst is 5 seconds to 100 seconds, so as to perform a catalytic cleavage reaction. The ionic liquid catalyst is in a liquid phase. The ionic liquid catalyst includes tributylalkyl phosphonium halide, and the alkyl includes an alkyl group having 3 to 16 carbon atoms.
Efficient Electrocatalysis for the Preparation of (Hetero)aryl Chlorides and Vinyl Chloride with 1,2-Dichloroethane
Liang, Yujie,Lin, Fengguirong,Adeli, Yeerlan,Jin, Rui,Jiao, Ning
supporting information, p. 4566 - 4570 (2019/02/14)
Although the application of 1,2-dichloroethane (DCE) as a chlorinating reagent in organic synthesis with the concomitant release of vinyl chloride as a useful byproduct is a fantastic idea, it still presents a tremendous challenge and has not yet been achieved because of the harsh dehydrochlorination conditions and the sluggish C?H chlorination process. Here we report a bifunctional electrocatalysis strategy for the catalytic dehydrochlorination of DCE at the cathode simultaneously with anodic oxidative aromatic chlorination using the released HCl as the chloride source for the efficient synthesis of value-added (hetero)aryl chlorides. The mildness and practicality of the protocol was further demonstrated by the efficient late-stage chlorination of bioactive molecules.
New method for synthesizing ranitidine
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Paragraph 0034-0036; 0047-049; 0059-0061, (2018/12/14)
The invention discloses a new method for synthesizing ranitidine. The method comprises the steps of synthesizing vinylidene chloride, synthesizing 1, 1-dichloro-2-nitroethylene, carrying out a ring-closing reaction, carrying out a ring-opening reaction in presence of a desiccant, and synthesizing the ranitidine. The method adopts an anhydrous environment in the preparation process of a ring-opening product, thus avoiding the interference with the reaction and the generation of impurities due to the presence of water, reducing the post-treatment work and increasing the utilization rate of the raw materials. The preparation method provided by the invention effectively increases the reaction yield of the ring-opening product, improves the purity of the ring-opening reaction, and reduces the reaction time; therefore, the yield and purity of the product ranitidine are improved, the production cost is lowered, and the method is more beneficial to industrial production.
Method for synthesizing ranitidine
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Paragraph 0034; 0035; 0045; 0046; 0056; 0057; 0067; 0068, (2017/10/09)
A method for synthesizing ranitidine includes following steps: 1), dropwise adding sodium hydroxide water solution into 1, 1, 2-trichloroethane at 30-35 DEG C for reaction to obtain vinylidene chloride, wherein a mass ratio of 1, 1, 2-trichloroethan to sodium hydroxide is 1:0.3-0.33; 2), dropwise adding vinylidene chloride into mixed acid of concentrated hydrochloric acid and concentrated nitric acid at 20-25 DEG C for reaction for 2-4h, wherein a consumption ratio of vinylidene chloride to the mixed acid is 1:2-3; 3), adding cysteamine hydrochloride into sodium hydroxide and potassium hydroxide solution, and dropwise adding a product of the step 2) at 50-55 DEG C to obtain a closed-loop product; 4), enabling the closed-loop product to react with alcohol or methanol solution at room temperature for 14-18h to obtain an open-loop product; 5), adding the open-loop product and 2-[(dimethylamino)methyl]-5 chloromethyl-furan into potassium hydroxide or sodium hydroxide water solution for reaction at 40-50 DEG C for 2-4h to obtain ranitidine. The method lowers potential safety hazards and is simple and easy for industrial production.
