220117-30-6Relevant academic research and scientific papers
Unmodified nano-powder magnetite catalyzes a four-component aza-Sakurai reaction
Martinez, Ricardo,Ramon, Diego J.,Yus, Miguel
experimental part, p. 1235 - 1240 (2009/05/30)
A new catalyst for an old material: magnetite is an excellent Lewis acid catalyst for the four-component aza-Sakurai reaction. The process could be repeated up to 15-times without losing effectiveness, with the catalyst recycling being as easy as the use of a simple magnet. The catalyst is selective and could discriminate between aldehyde and ketone functionalities, catalyzing first the reaction with the higher electrophilic aldehyde.
