22013-80-5

Upstream product

• 22013-79-2 1-(4-chlorophenyl)-1,2-dibromo-2-nitroethane 
• 706-07-0 1-chloro-4-(2-nitrovinyl)benzene 

Downstream Products

• 1198351-47-1 C₁₂H₁₀ClN₃O₄ 
• 1258432-42-6 (2R,3R)-3-(4-chlorophenyl)-2-nitro-2H-furo[3,2-c]chromen-4(3H)-one 
• 1258432-47-1 (2R,3R)-3-(4-chlorophenyl)-8-methyl-2-nitro-2H-furo[3,2-c]chromen-4(3H)-one 
• 1258432-54-0 (2R,3R)-3-(4-chlorophenyl)-2-nitro-2,3,6,7-tetrahydrobenzofuran-4(5H)-one 
• 1258432-57-3 (2R,3R)-3-(4-chlorophenyl)-6,6-dimethyl-2-nitro-2,3,6,7-tetrahydrobenzofuran-4(5H)-one 
• 1258432-59-5 (4R,5R)-methyl-4-(4-chlorophenyl)-2-methyl-5-nitro-4,5-dihydrofuran-3-carboxylate 
• 1258432-61-9 1-((4R,5R)-4-(4-chlorophenyl)-2-methyl-5-nitro-4,5-dihydrofuran-3-yl)ethanone 
• 132784-93-1 3-(4-chlorophenyl)-2-nitro-3,5,6,7-tetrahydro-4(2H)-benzofuranone 

Relevant academic research and scientific papers

Palladium-Catalyzed Formal (3 + 2) Cycloaddition Reactions of 2-Nitro-1,3-enynes with Vinylaziridines, -epoxides, and -cyclopropanes

A two-step Pd-catalyzed (3 + 2) cycloaddition/HNO2 elimination reaction sequence has been developed to give novel cyclic 1,3-dien-5-yne systems from Pd-stabilized zwitterionic 1,3-dipoles and 2-nitro-1,3-enyne substrates. The process is highly atom-efficient and tolerates the reaction of 2-vinyloxirane, 1-tosyl-2-vinylaziridine, and diethyl 2-vinylcyclopropane-1,1-dicarboxylate derived 1,3-dipoles with a variety of 2-nitro-1,3-enyne substrates. The stereochemistry of the intermediate (3 + 2) cycloadducts was determined by single crystal X-ray analysis. Furthermore, a selective kinetic elimination of the cycloadduct with an antiperiplanar relationship between the NO2 group and the participating hydrogen was demonstrated, allowing for efficient isolation of a single diastereoisomer of the cycloadduct.

Organocatalytic Asymmetric Synthesis of Aza-Spirooxindoles via Michael/Friedel-Crafts Cascade Reaction of 1,3-Nitroenynes and 3-Pyrrolyloxindoles

An asymmetric [3+3] cyclization of nitroenynes and 3-pyrrolyloxindoles has been realized with a chiral bifunctional squaramide catalyst. This Michael/Friedel-Crafts cascade strategy provides a facile and efficient access to enantioenriched polycyclic aza-spirooxindoles with 32-95% isolated yields and excellent stereocontrol under mild reaction conditions.

Cinnamic acid derivative and preparation method and application thereof

The invention provides a cinnamic acid derivative. The cinnamic acid derivative is of the structure as shown in the formula I. The invention also provides two methods for preparing the cinnamic acid derivative. The two methods depend on a single bond or double bonds in the structure shown in the formula I. The invention further provides a pesticide. The pesticide comprises the cinnamic acid derivative. In addition, the invention provides a sterilization method. The sterilization method includes the step of applying the cinnamic acid derivative or the pesticide to crops. The crops include rice,wheat, fruit trees and vegetables. The low-toxicity, low-residue-content and high-activity environment-friendly cinnamic acid derivative is developed, and the cinnamic acid derivative pesticide can replace traditional high-toxicity and high-residue-content pesticides.