220178-53-0Relevant academic research and scientific papers
Stereoselective synthesis of enantiomerically pure β-fluoroalkyl γ- butyrolactones by sulfoxide-directed lactonization
Bravo, Pierfrancesco,Arnone, Alberto,Bandiera, Paola,Bruche?, Luca,Ohashi, Yuji,Ono, Taizo,Sekine, Akiko,Zanda, Matteo
, p. 111 - 115 (1999)
Enantiomerically pure α,α-dichloro β-fluoroalkyl γ-p-tolylthio γ- butyrolactones trans-6a-c have been obtained with excellent stereocontrol (> 98:2) and enantiomeric purity (> 98:2) by sulfoxide-directed lactonization (Marino's annulation reaction) of β-f
