220182-72-9

Upstream product

• 67-56-1 methanol 
• 220182-68-3 4-(1-bromoethyl)-1-t-butoxycarbonyl-1,5-dihydro-3-methyl-5-tosyl-2H-pyrrol-2-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 263898-71-1 5-acetoxy-5-(t-butoxycarbonyl)-4-ethyl-1,5-dihydro-3-methyl-2H-pyrrol-2-one 
• 220182-64-9 1-t-butoxycarbonyl-4-ethyl-1,5-dihydro-3-methyl-5-tosyl-2H-pyrrol-2-one 
• 152796-98-0 4-ethyl-3-methyl-5-(p-toluenesulfonyl)-1,5-dihydro-1H-pyrrolin-2-one 
• 108785-03-1 tert-butyl 3-ethyl-5-iodo-4-methylpyrrole-2-carboxylate 
• 75488-16-3 tert-Butyl-(3-ethyl-4-methyl-pyrrolyl-2)-methanoat 

Downstream Products

• 220182-46-7 4-(1-methoxyethyl)-3-methyl-5-tosyl-1,5-dihydro-2H-pyrrol-2-one 
• 16883-97-9 phycocyanobilin 

Relevant academic research and scientific papers

An efficient method to construct the A,B-rings component toward total syntheses of phycocyanobilin and its derivative as a photoprobe

Total syntheses of physocyanobilin and its derivative bearing a photoreactive group at the D-ring accomplished by developing a new and efficient method for the construction of A,B-rings component, which consists of the Wittig-type new coupling reaction of 4-(1-methoxyethyl or 1- tosylethyl)-3-methyl-5-tosyl-1,5-dihydro-2H-pyrrol-2-one and a 2-formyl pyrrole derivative in the presence of (n)Bu3P and a base, followed by reduction with aluminum amalgam and a subsequent acid or base treatment.

Efficient construction of A,B-rings component for syntheses of phycocyanobilin and its derivative

Total syntheses of phycocyanobilin and its photoactivatable derivative were accomplished by developing a new and versatile method for the construction of A,B-rings component, which consists of the Wittig-type new coupling reaction of 4-(1-methoxyethyl) -3