220185-36-4

Basic information

• Product Name: 1,3-BIS[BIS(3,5-DIMETHYLPHENYL)PHOSPHINO]PROPANE
• Synonyms: 1,3-BIS[BIS(3,5-DIMETHYLPHENYL)PHOSPHINO]PROPANE
• CAS NO: 220185-36-4
• Molecular Formula: C₃₅H₄₂P₂
• Molecular Weight: 524.66
• Mol File: 220185-36-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-BIS[BIS(3,5-DIMETHYLPHENYL)PHOSPHINO]PROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-BIS[BIS(3,5-DIMETHYLPHENYL)PHOSPHINO]PROPANE(220185-36-4)
• EPA Substance Registry System: 1,3-BIS[BIS(3,5-DIMETHYLPHENYL)PHOSPHINO]PROPANE(220185-36-4)

Safety Data

• Hazardous Substances Data: 220185-36-4(Hazardous Substances Data)

Usage

Type of Compound

Chemical compound

Role

Used as a ligand in coordination chemistry

Classification

Diphosphine ligand

Structure

Two phosphine functional groups attached to a central propane backbone

Applications

Commonly used in catalytic processes

Industries

Synthesis of pharmaceuticals and fine chemicals

Benefits

Unique structure and properties make it an effective ligand for promoting and controlling various chemical reactions

Reactions

Hydrogenation, cross-coupling, and C-H activation

Potential Applications

Catalyzing sustainable and environmentally friendly chemical transformations.

Upstream product

• 28240-70-2 1,3-Propandiylbis(dichlorphosphan) 
• 34696-73-6 3,5-dimethyphenylmagnesium bromide 
• 187344-92-9 bis(3,5-dimethylphenyl)phosphine oxide 
• 556-96-7 5-bromo-1,3-xylene 

Relevant articles and documents

Development of effective bidentate diphosphine ligands of ruthenium catalysts toward practical hydrogenation of carboxylic acids

Hydrogenation of carboxylic acids (CAs) to alcohols represents one of the most ideal reduction methods for utilizing abundant CAs as alternative carbon and energy sources. However, systematic studies on the effects of metal-to-ligand relationships on the catalytic activity of metal complex catalysts are scarce. We previously demonstrated a rational methodology for CA hydrogenation, in which CA-derived cationic metal carboxylate [(PP)M(OCOR)]+ (M = Ru and Re; P = one P coordination) served as the catalyst prototype for CA self-induced CA hydrogenation. Herein, we report systematic trial- and-error studies on how we could achieve higher catalytic activity by modifying the structure of bidentate diphosphine (PP) ligands of molecular Ru catalysts. Carbon chains connecting two P atoms as well as Ar groups substituted on the P atoms of PP ligands were intensively varied, and the induction of active Ru catalysts from precatalyst Ru(acac)3 was surveyed extensively. As a result, the activity and durability of the (PP)Ru catalyst substantially increased compared to those of other molecular Ru catalyst systems, including our original Ru catalysts. The results validate our approach for improving the catalyst performance, which would benefit further advancement of CA self-induced CA hydrogenation.