22019-68-7Relevant academic research and scientific papers
Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation
Cil, Onur,Phuan, Puay-Wah,Son, Jung-Ho,Zhu, Jie S.,Ku, Colton K.,Tabib, Niloufar Akhavan,Teuthorn, Andrew P.,Ferrera, Loretta,Zachos, Nicholas C.,Lin, Ruxian,Galietta, Luis J.V.,Donowitz, Mark,Kurth, Mark J.,Verkman, Alan S.
, p. 14 - 4,26 (2017/03/22)
Constipation is a common condition for which current treatments can have limited efficacy. By high-throughput screening, we recently identified a phenylquinoxalinone activator of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan
PROTEIN KINASE INHIBITORS
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Page/Page column 68, (2010/11/28)
Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
Fused bicyclic mTOR inhibitors
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Page/Page column 68, (2008/06/13)
Compounds represented by Formula (I) or a pharmaceutically acceptable salt thereof, are inhibitors of mTOR and useful in the treatment of cancer.
