22022-30-6

Usage

Uses

Used in Chemical Synthesis:
Cyclopentanol, 2-ethynyl(8CI, 9CI) is used as a reagent in chemical reactions for the synthesis of other organic compounds. Its unique structure and properties make it a valuable component in the creation of various chemical products.
Used in Research and Development:
In the field of research and development, Cyclopentanol, 2-ethynyl(8CI, 9CI) serves as a key compound for studying chemical reactions and exploring new methods for synthesizing organic compounds. Its potential applications in creating novel chemical entities make it an important substance for scientific investigation.
Used in Pharmaceutical Industry:
Cyclopentanol, 2-ethynyl(8CI, 9CI) may be utilized in the pharmaceutical industry for the development of new drugs and medicinal compounds. Its unique properties could contribute to the creation of innovative therapeutic agents.
Used in Chemical Reagent Industry:
As a reagent, Cyclopentanol, 2-ethynyl(8CI, 9CI) is used in the chemical reagent industry to facilitate various chemical processes. Its role in these processes is essential for the production of a wide range of chemical products.

Upstream product

• 82031-95-6 1,1,2,2,3,3,4,4,4-Nonafluoro-butane-1-sulfonic acid (1R,2S)-2-ethynyl-cyclopentyl ester 
• 34329-47-0 1,2-epoxy-1-ethynyl-cyclopentane 
• 79938-01-5 2-ethynylcyclopentyl formate 
• 57857-90-6 (+/-)-trans-2-iodocyclopentanol 
• 61967-50-8 trans-2-Ethynylcyclopentan-1-ol 
• 285-67-6 Cyclopentene oxide 
• 75-89-8 2,2,2-trifluoroethanol 

Downstream Products

• 61747-55-5 rac-(3aR,6aR)-3-methylenehexahydro-2H-cyclopenta[b]furan-2-one 
• 54133-77-6 cis-2-oxabicyclo<4.3.0>non-4-en-3-one 

Relevant academic research and scientific papers

Gold-catalyzed rearrangement of allylic oxonium ylides: Efficient synthesis of highly functionalized dihydrofuran-3-ones

"Diazo" not needed: The title reaction results in the rearrangement of oxonium ylides, which were prepared from readily available homopropargylic allylic ethers instead of diazo compounds, through two different mechanisms: a concerted 2,3-sigmatropic rearrangement, or a stepwise 1,4-allyl migration followed by a Claisen rearrangement (see scheme). Copyright

The first radical method for the introduction of an ethynyl group using a silicon tether and its application to the synthesis of 2′-deoxy-2′-C-ethynylnucleosides

A novel radical method for the stereoselective introduction of an ethynyl group has been developed. When a solution of ethynyldimethylsilyl (EDMS) or [2-(trimethylsilyl)ethynyl]dimethylsilyl (TEDMS) ethers of trans-2-iodoindanol was treated with Et3

Substituent effects on the SmI2/Pd(0)-promoted carbohydrate ring-contraction of 5-alkynylpyranosides

The effect of substituents on the reactivity and stereoselectivity of the SmI2/Pd(0)-promoted ring-contraction of 5-alkynylpyranosides has been examined using substrates substituted only at selected positions. While formation of 2-ethynylcyclopentanols takes place efficiently, an internal alkyne did not afford the expected product. The presence of peripheral alkoxy substituents leads to variable stereoselectivities that depend on the number and orientation of such groups. Thus, an isolated OBn substituent at C(3) (carbohydrate numbering) exerts a significant stereochemical control while additional substitution with the same group at C(4) either enhances or drastically reduces stereoselectivity depending on its orientation (α or β, respectively).

Vinyl Cations, 37. Rearrangement of Cyclic Homopropargyl Sulfonates to Condensed Cyclobutanones and Cyclopropyl Ketones

Cyclic homopropargyl sulfonates 8 (tosylates, triflates, nonaflates, and damsylates) are prepared and solvolysed.The resulting rearrangement reactions are studied with respect to the properties of the solvents used, leaving groups, the substituent on the triple bond, and with respect to the ring size of the sulfonates 8.