220227-84-9 Usage
Uses
Used in Pharmaceutical Industry:
3-(Trifluoromethoxy)benzenesulfonyl chloride is used as a reagent in the synthesis of pharmaceuticals for its ability to introduce the trifluoromethoxy functional group, which can enhance the pharmacological properties of drug molecules.
Used in Agrochemical Industry:
In the agrochemical industry, 3-(Trifluoromethoxy)benzenesulfonyl chloride is utilized as a reagent in the production of agrochemicals, where its strong electrophilic nature aids in the synthesis of various agrochemical compounds.
Used in Organic Synthesis:
3-(Trifluoromethoxy)benzenesulfonyl chloride is used as a key intermediate in the preparation of various functionalized sulfonyl compounds, playing a crucial role in chemical transformations and the development of new organic compounds.
Used in Chemical Research:
As a strong electrophile, 3-(Trifluoromethoxy)benzenesulfonyl chloride is employed in chemical research to explore its reactivity and potential applications in the synthesis of novel organic molecules and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 220227-84-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,2,2 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 220227-84:
(8*2)+(7*2)+(6*0)+(5*2)+(4*2)+(3*7)+(2*8)+(1*4)=89
89 % 10 = 9
So 220227-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H4ClF3O3S/c8-15(12,13)6-3-1-2-5(4-6)14-7(9,10)11/h1-4H
220227-84-9Relevant academic research and scientific papers
Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids
Debergh, J. Robb,Niljianskul, Nootaree,Buchwald, Stephen L.
supporting information, p. 10638 - 10641 (2013/08/23)
A palladium-catalyzed method for the preparation of sulfonamides is described. The process exhibits significant functional group tolerance and allows for the preparation of a number of arylsulfonyl chlorides and sulfonamides under mild conditions.
Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists
-
, (2008/06/13)
The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.
