220271-61-4

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 220271-55-6 [(E)-2-(2,2-Bis-benzenesulfonyl-ethyl)-5-furan-3-yl-4-(tetrahydro-pyran-2-yloxy)-pent-2-enyloxy]-tert-butyl-dimethyl-silane 
• 220271-56-7 (E)-2-(2,2-Bis-benzenesulfonyl-ethyl)-5-furan-3-yl-4-(tetrahydro-pyran-2-yloxy)-pent-2-en-1-ol 
• 220271-54-5 (E)-6,6-Bis-benzenesulfonyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-1-furan-3-yl-hex-3-en-2-ol 
• 220271-59-0 (Z)-8-(tert-Butyl-dimethyl-silanyloxy)-2,6-dimethyl-oct-2-en-1-ol 
• 220271-58-9 6-(tert-butyldimethylsilanyloxy)-4-methylhexanal 
• 87921-26-4 tert-butyl((3,7-dimethyloct-6-en-1-yl)oxy)dimethylsilane 
• 3406-02-8 bis(phenylsulfonyl)methane 
• 106-22-9 Citronellol 
• 220271-60-3 ((Z)-8-Bromo-3,7-dimethyl-oct-6-enyloxy)-tert-butyl-dimethyl-silane 
• 1025938-02-6 4-(2,2-Bis-benzenesulfonyl-ethyl)-2-furan-3-ylmethyl-furan 

Relevant academic research and scientific papers

Palladium catalyzed synthesis of the furanoterpene ircinin-4

A flexible entry into 2,4-disubstituted furan derivatives is outlined employing sulfonium salt 1 as a well accessible starting material. Condensation of the sulfur ylide derived from 1 with aldehydes, palladium catalyzed opening of the vinyloxirane thus formed, and a final oxidative cyclization of the furan ring constitute the key steps of this method. Its utility is exemplified by the first total synthesis of the marine natural product ircinin-4 (2).