220337-58-6

Basic information

• Product Name: N-(3-hydroxypropyl)-2-sulfanylacetamide
• Synonyms: acetamide, N-(3-hydroxypropyl)-2-mercapto-; N-(3-Hydroxypropyl)-2-sulfanylacetamide
• CAS NO: 220337-58-6
• Molecular Formula: C₅H₁₁NO₂S
• Molecular Weight: 149.2113
• Mol File: 220337-58-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 382.5°C at 760 mmHg
• Flash Point: 185.1°C
• Density: 1.16g/cm³
• Vapor Pressure: 2.01E-07mmHg at 25°C
• Refractive Index: 1.507
• CAS DataBase Reference: N-(3-hydroxypropyl)-2-sulfanylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-hydroxypropyl)-2-sulfanylacetamide(220337-58-6)
• EPA Substance Registry System: N-(3-hydroxypropyl)-2-sulfanylacetamide(220337-58-6)

Safety Data

• Hazardous Substances Data: 220337-58-6(Hazardous Substances Data)

Upstream product

• 2365-48-2 Methyl thioglycolate 
• 156-87-6 propan-1-ol-3-amine 

Relevant articles and documents

Agent and method for permanent shaping of hair and method for the production of N-alkylmercaptoacetamides

The aqueous ready-to-apply composition for permanent waving of hair has a pH of 4 to 8.5 and from 3 to 28% by weight of at least one N-alkylmercaptoacetamide of formula (I): wherein R represents a straight-chain alkyl group having from 3 to 6 carbon atoms or a straight-chain hydroxyalkyl group having from 3 to 6 carbon atoms; or a salt thereof; and at least one standard cosmetic additive ingredient, such as thickeners, wetting agents and emulsifiers, perfume oils, conditioners and buffer substances. The ready-to-apply composition can be made by mixing two or more components, one of which contains the N-alkylmercaptoacetamide. A method for permanent waving of hair using the ready-to-apply composition is also described. A process for making the N-alkylmercapto-acetamides includes reacting a suitable amine with methylthioglycolate under a protective gas atmosphere at temperatures that are not greater than 30° C.