156-87-6Relevant articles and documents
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Wiley
, p. 1867 (1946)
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Method for preparing gamma-aminopropanol through one-step catalytic hydrogenation and application of gamma-aminopropanol
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Paragraph 0011-0018, (2021/07/17)
The invention relates to a method for preparing gamma-aminopropanol through one-step catalytic hydrogenation, which comprises the following step: in the presence of a metal catalyst, beta-alanine and hydrogen are subjected to hydrogenation reaction in a reaction solvent to obtain gamma-aminopropanol. The method has the advantages that the yield is high, the purity of the prepared gamma-aminopropanol is high, the operation is simple and convenient, the raw materials are cheap and easy to obtain, the method is safe and controllable, the method is green and environment-friendly, the cost is better, the method is suitable for industrial production and the like, and the quality, the yield, the effectiveness and the safety of the product prepared from the gamma-aminopropanol are remarkably improved.
Catalyst for producing 3-aminopropanol by hydrogenating 3-hydroxypropionitrile and preparation method thereof
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Paragraph 0110; 0111; 0116-0118; 0126, (2020/06/09)
The invention discloses a catalyst for producing 3-aminopropanol by hydrogenating 3-hydroxypropionitrile. The catalyst is characterized in that the catalyst comprises an active component and a carrier, wherein the active component comprises active metal elements; the active metal elements comprise M and Re; M is selected from at least one of Ni, Co and Cu; M accounts for 5.0-50.0% of the weight ofthe catalyst; Re accounts for 0.1-15.0% of the weight of the catalyst; and the carrier is selected from at least one of inorganic porous materials. The catalyst has high catalytic activity and selectivity.
Organocatalytic Decarboxylation of Amino Acids as a Route to Bio-based Amines and Amides
Claes, Laurens,Janssen, Michiel,De Vos, Dirk E.
, p. 4297 - 4306 (2019/08/26)
Amino acids obtained by fermentation or recovered from protein waste hydrolysates represent an excellent renewable resource for the production of bio-based chemicals. In an attempt to recycle both carbon and nitrogen, we report here on a chemocatalytic, metal-free approach for decarboxylation of amino acids, thereby providing a direct access to primary amines. In the presence of a carbonyl compound the amino acid is temporarily trapped into a Schiff base, from which the elimination of CO2 may proceed more easily. After evaluating different types of aldehydes and ketones on their activity at low catalyst loadings (≤5 mol%), isophorone was identified as powerful organocatalyst under mild conditions. After optimisation many amino acids with a neutral side chain were converted in 28–99 % yield in 2-propanol at 150 °C. When the reaction is performed in DMF, the amine is susceptible to N-formylation. This consecutive reaction is catalysed by the acidity of the amino acid reactant itself. In this way, many amino acids were efficiently transformed to the corresponding formamides in a one-pot catalytic system.
