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Cyclopropanamine, 2-(3-fluorophenyl)-, (1R,2S)(9CI) is a chemical compound with a unique molecular structure, characterized by a cyclopropane ring and a fluorophenyl group. It is an impurity found in Ticagrelor, a medication used for the treatment of acute coronary syndromes (ACS).

220353-83-3

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220353-83-3 Usage

Uses

Used in Pharmaceutical Industry:
Cyclopropanamine, 2-(3-fluorophenyl)-, (1R,2S)(9CI) is used as an impurity in the production of Ticagrelor (T437700) for the treatment of acute coronary syndromes (ACS). Its presence in the medication is controlled and monitored to ensure the safety and efficacy of the drug. The compound plays a role in the development and manufacturing process of Ticagrelor, contributing to its overall therapeutic effects in managing ACS.

Check Digit Verification of cas no

The CAS Registry Mumber 220353-83-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,3,5 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 220353-83:
(8*2)+(7*2)+(6*0)+(5*3)+(4*5)+(3*3)+(2*8)+(1*3)=93
93 % 10 = 3
So 220353-83-3 is a valid CAS Registry Number.

220353-83-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Cyclopropanamine, 2-(3-fluorophenyl)-, (1R,2S)- (9CI)

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:220353-83-3 SDS

220353-83-3Relevant academic research and scientific papers

Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase

Li, Huiying,Xue, Fengtian,Kraus, James M.,Ji, Haitao,Labby, Kristin Jansen,Mataka, Jan,Delker, Silvia L.,Martásek, Pavel,Roman, Linda J.,Poulos, Thomas L.,Silverman, Richard B.

, p. 1333 - 1343 (2013/03/28)

Inhibitors of neuronal nitric oxide synthase have been proposed as therapeutics for the treatment of different types of neurological disorders. On the basis of a cis-3,4-pyrrolidine scaffold, a series of trans-cyclopropyl- and methyl-containing nNOS inhib

POTENT AND SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS WITH IMPROVED MEMBRANE PERMEABILITY

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Page/Page column 30, (2010/08/08)

Compounds and related compositions and methods as can be used to inhibit neuronal nitric oxide synthase and as can be employed in the treatment of various neurodegenerative diseases.

Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors with Improved Membrane Permeability

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, (2010/08/07)

Compounds and related compositions and methods as can be used to inhibit neuronal nitric oxide synthase and as can be employed in the treatment of various neurodegenerative diseases.

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