350-51-6

Basic information

• Product Name: 3-Fluorostyrene
• Synonyms: 1-ethenyl-3-fluorobenzene;1-Fluoro-3-vinylbenzene;3-FLUOROSTYRENE;M-FLUOROSTYRENE;3-Fluorostyrene 98%;3-Fluorostyrene98%;3-FLUOROSTYRENE , STABILIZED WITH 0.1% 4-TERT-BUTYLCATECHOL;3-Fluorostyrene, 97%, stab. with 0.1% 4-tert-butylcatechol
• CAS NO: 350-51-6
• Molecular Formula: C₈H₇F
• Molecular Weight: 122.14
• EINECS: 206-504-9
• Product Categories: Styrenes;monomer;Monomers;Polymer Science;Styrene and Functionalized Styrene Monomers;Fluorine series
• Mol File: 350-51-6.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 30-31 °C4 mm Hg(lit.)
• Flash Point: 85 °F
• Appearance: clear colorless liquid
• Density: 1.025 g/mL at 25 °C(lit.)
• Vapor Pressure: 2.97mmHg at 25°C
• Refractive Index: n20/D 1.517(lit.)
• Storage Temp.: 0-6°C
• Water Solubility: Insoluble in water
• BRN: 2038488
• CAS DataBase Reference: 3-Fluorostyrene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Fluorostyrene(350-51-6)
• EPA Substance Registry System: 3-Fluorostyrene(350-51-6)

Safety Data

• Hazard Codes: Xi,F
• Statements: 10-36-36/37/38
• Safety Statements: 16-26-33-37/39
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 350-51-6(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless liquid

InChI:InChI=1/C8H7F/c1-2-7-4-3-5-8(9)6-7/h2-6H,1H2

Upstream product

• 17318-03-5 bromo(3-fluorophenyl)magnesium 
• 108-05-4 vinyl acetate 
• 1073-06-9 3-fluorobromobenzene 
• 201230-82-2 carbon monoxide 
• 2561-17-3 1-ethynyl-3-fluoro-benzene 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 456-48-4 3-Fluorobenzaldehyde 
• 402-63-1 1-(3-fluorophenyl)ethanol 
• 1868-53-7 dibromofluoromethane 
• 765-46-8 spiro[2.4]hepta-4,6-diene 
• 84648-19-1 C₁₆H₁₂ClFO₄ 
• 20595-30-6 3-fluorocinnamic acid 

Downstream Products

• 70372-47-3 Acetic acid 1-(3-fluoro-phenyl)-2-thiocyanato-ethyl ester 
• 115665-64-0 2-Brom-1-(3-fluor-phenyl)-ethylen 
• 6908-41-4 4-(methoxycarbonyl)benzyl alcohol 
• 633327-36-3 (E)-2-(3-fluorostyryl)-4,4,5,5-tetramethyl-1,3-dioxa-2-borolane 
• 354809-28-2 5,7-dichloro-4-(3-fluorophenyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid ethyl ester 
• 354809-48-6 5,7-dichloro-4-(3-fluorophenyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid 
• 263893-75-0 ethyl 2-(3-fluorophenyl)cyclopropane carboxylate 
• 168911-80-6 [Pt(η(2)-CH2=CHC6H4F-3)(Bu(t)2P(CH2)3PBu(t)2)] 
• 1166996-26-4 1-(3-fluorophenyl)-2-(tetrahydrofuran-2-yl)ethanone 
• 1166996-40-2 2-(1,3-dioxolan-2-yl)-1-(3-fluorophenyl)ethanone 
• 1421521-03-0 (E)-1-[3,3-difluoro-3-(phenylsulfonyl)prop-1-en-1-yl]-3-fluorobenzene 
• 1157561-41-5 rac-trans-2-(3-fluorophenyl)-cyclopropanecarboxylic acid 
• 696-39-9 1-fluoro-3-ethylbenzene 
• 1610769-52-2 N-(2-chloro-2-(3-fluorophenyl)ethyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

Nickel-Catalyzed Reductive Cross-Coupling of Aryl Bromides with Vinyl Acetate in Dimethyl Isosorbide as a Sustainable Solvent

A nickel-catalyzed reductive cross-coupling has been achieved using (hetero)aryl bromides and vinyl acetate as the coupling partners. This mild, applicable method provides a reliable access to a variety of vinyl arenes, heteroarenes, and benzoheterocycles, which should expand the chemical space of precursors to fine chemicals and polymers. Importantly, a sustainable solvent, dimethyl isosorbide, is used, making this protocol more attractive from the point of view of green chemistry.

Copper-Catalyzed Sulfonylation of Cyclobutanone Oxime Esters with Sulfonyl Hydrazides

A copper-catalyzed radical cross-coupling of cyclobutanone oxime esters with sulfonyl hydrazides has been developed. The copper-based catalytic system proved crucial for cleavage of the C-C bond of cyclobutanone oximes and for selective C-S bond-formation involving persistent sulfonyl-metal radical intermediates. This protocol is distinguished by the low-cost catalytic system, which does not require ligand, base, or toxic cyanide salt, and by the use of readily accessible starting materials, as well as broad substrate scope, providing an efficient approach to various diversely substituted cyano-containing sulfones.

Towards nitrile-substituted cyclopropanes-a slow-release protocol for safe and scalable applications of diazo acetonitrile

Diazo acetonitrile has long been neglected despite its high value in organic synthesis due to a high risk of explosions. Herein, we report our efforts towards the transient and safe generation of this diazo compound, its applications in iron catalyzed cyclopropanation and cyclopropenation reactions and the gram-scale synthesis of cyclopropyl nitriles.