220358-50-9Relevant articles and documents
Intramolecular 1,5-hydrogen atom transfer radical reaction of pyrrolidine derivatives
Ishizaki, Miyuki,Takano, Hideaki,Hoshino, Osamu
, p. 305 - 314 (2007/10/03)
Intramolecular 1,5-hydrogen atom transfer radical cyclization reaction of pyrrolidine derivatives was examined. Radical reaction of 3,4-bis(α,β- unsaturated acyloxy)-(8, 9) and 3,4-diacetoxy (13)-N-[(o- halobenzyl)pyrrolidines underwent elimination of two acyloxy groups to give mainly N-benzylpyrrole (11). On the other hand, the similar reaction of 3,4- diallyloxy-N-(o-bromobenzyl)pyrrolidine (16) gave desired hexahydrofuro[3,2- b]pyrroles (17, 18) together with a dimeric hexahydrofuro[3,2-b]pyrrole (19).