220384-68-9

Basic information

• Product Name: 1-(p-toluenesulfonyl)-piperidin-3-ol
• Synonyms: 1-(p-toluenesulfonyl)-piperidin-3-ol
• CAS NO: 220384-68-9
• Molecular Weight: 255.338
• Mol File: 220384-68-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-(p-toluenesulfonyl)-piperidin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(p-toluenesulfonyl)-piperidin-3-ol(220384-68-9)
• EPA Substance Registry System: 1-(p-toluenesulfonyl)-piperidin-3-ol(220384-68-9)

Safety Data

• Hazardous Substances Data: 220384-68-9(Hazardous Substances Data)

Upstream product

• 81097-24-7 N-tosyl-(4-pentenyl)amine 
• 6859-99-0 3-hydroxypiperazine 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 98-59-9 p-toluenesulfonyl chloride 
• 64051-79-2 piperidin-3-ol hydrochloride 

Downstream Products

• 1335248-27-5 (R)-1-tosylpiperidin-3-yl acetate 
• 1126736-18-2 (S)-N-tosyl-3-hydroxypiperidine 
• 56293-29-9 (+)-aloperine 
• 220384-61-2 (6R,7R,13R,14R,15S)-14-hydroxy-1-(p-toluenesulfonyl)-tetradecahydro-6,13-methano-dipyrido<1,2-a;3',2'-e>azocin-12-one 
• 220384-63-4 (6R,7R,13S,15S)-1-(p-toluenesulfonyl)-tetradecahydro-6,13-methano-dipyrido<1,2-a;3',2'-e>azocin-12-one 
• 220384-57-6 (2R)-2-<(1E)-2-<1-(p-toluenesulfonyl)-1,4,5,6-tetrahydropyridin-3-yl>-vinyl>-piperidine-1-carboxylic acid tert-butyl ester 
• 220384-58-7 5-((E)-(R)-2-Piperidin-2-yl-vinyl)-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridine 
• 220384-56-5 trifluoromethanesulfonic acid 1-(p-toluenesulfonyl)-1,4,5,6-tetrahydro-pyridin-3-yl ester 
• 19748-93-7 1-propyl-3-phenyl-piperidine 
• 344257-61-0 3-(4-methoxyphenyl)-1-propylpiperidine 
• 86562-23-4 (+/-)-3-(3-methoxyphenyl)-N-n-propylpiperidine 
• 75240-91-4 1-propyl-3-(3-hydroxyphenyl)piperidine 
• 79601-21-1 3-(3-methoxyphenylpiperidine) 

Relevant articles and documents

Metal-free synthesis of sulfonamides via iodine-catalyzed oxidative coupling of sulfonyl hydrazides and amines

A novel, rapid, and environmentally-friendly protocol for the synthesis of sulfonamides using iodine as catalyst under solvent-free conditions is described. This method involves the oxidative coupling of sulfonyl hydrazides and amines in the presence of catalytic amount of iodine using TBHP as oxidant. This protocol does not require purification techniques such as column chromatography and recrystalization.

Flexible gold-catalyzed regioselective oxidative difunctionalization of unactivated alkenes

AuI/AuIII catalytic cycles can trigger three highly regioselective alkene difunctionalization processes that involve the formation of C(sp3)iO, C(sp3)iN, and C(sp3)iC(sp 2) bonds. The react

Concise synthesis of 3-arylpiperidines

We present an easy and straightforward synthesis of 3-arylpiperidines by Grignard addition of piperidin-3-one with different arylmagnesium bromide reagents and acidic dehydroxylation of the resulting tertiary alcohol with the combination of triethylsilane and boron trifluoride etherate. This facile strategy was further used to synthesize preclamol. A highly regioselective dehydration of 3-arylpiperidin-3-ol with boron trifluoride etherate was investigated for preparing 3-aryl-1,4,5,6-tetrahydropyridine skeleton. A novel selenium dioxide mediated dihydroperoxidation of 3-aryl-1,4,5,6-tetrahydropyridine was also examined.