220435-48-3Relevant academic research and scientific papers
Quinic acid derivative and preparation method and application thereof
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Paragraph 0138; 0146; 0149; 0150, (2019/10/01)
The invention discloses a quinic acid derivative and a preparation method and application thereof. The quinic acid derivative has a structure represented by a formula I, wherein R1, R2 and R3 are OH or AcNH; R1 = OH, R2 = R3 = AcNH, or R2 = OH, R1 = R3 = AcNH, or R3 = OH, R1 = R2 = AcNH; * represents an R configuration or an S configuration; and Ac represents caffeoyl CAc or a derivative caffesulfonyl SAc, and coffee(mono-methyl ester)phosphonyl PAc. The quinic acid derivative has the advantages of mild preparation conditions, simple and safe operation, high product purity and relatively hightotal yield, and the obtained quinic acid derivative can be used for preparing medicaments for treating viral infections, especially for preparing medicaments for treating influenza virus, parainfluenza virus and respiratory syncytial virus infections.
CAFFEOYL QUINIC ACID DERIVATIVES CONTAINING NITROGEN, AND PREPARATION METHOD, PHARMACEUTICALLY COMPOSITION AND USAGE THEREOF
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Page/Page column 9, (2009/12/23)
The present invention provides caffeoylquinic acid derivatives and a method of preparing for the same, and also provides pharmaceutical compositions containing caffeoylquinic acid derivatives, and uses of caffeoylquinic acid derivatives in preparation of
