220436-00-0Relevant articles and documents
One-pot oxidation and rearrangement of propargylamines and in situ pyrazole synthesis
Chen, Jinshan,Properzi, Roberta,Uccello, Daniel P.,Young, Jennifer A.,Dushin, Russell G.,Starr, Jeremy T.
supporting information, p. 4146 - 4149 (2014/09/29)
Reported here are procedures for a one-pot oxidation and rearrangement of propargylamines to synthesize enaminones, with supporting mechanistic studies. Also reported are the extended one-pot syntheses of pyrazoles, including celecoxib and various heterocyclic compounds.