220445-43-2Relevant academic research and scientific papers
Potential metabolites of a condensed 2,3-benzodiazepine derivative
Csuzdi, Emese,Migleczi, Katalin,Hazai, Istvan,Berzsenyi, Pal,Pallagi, Istvan,Horvath, Gyula,Lengyel, Gyoergy,Solyom, Sandor
, p. 4662 - 4665 (2007/10/03)
Putative metabolites of an AMPA antagonist imidazo-2,3-benzodiazepine (2) were synthesized and compared to constituents formed from the parent compound by a rat liver perfusion method. As metabolic transformations, hydroxylation of the 2-methyl group and
