220451-65-0Relevant academic research and scientific papers
Nitroalkenes as carbonyl surrogates in arylmethyl-homoallylic alcohol forming one-pot allylation reactions in water
Lin, Mei-Huey,Lin, Wei-Cheng,Liu, Han-Jun,Chuang, Tsung-Hsun
, p. 1278 - 1282 (2013/03/28)
A simple and practical approach has been developed for conducting direct, homoallylic alcohol forming allylation reactions of nitroalkenes in water. Employing the new method, various arylmethyl-homoallylic alcohols can be produced from the corresponding, readily prepared β-nitrostyrenes.
Diastereoselective intramolecular meta photocycloaddition of side-chain- substituted 5-(2-methoxyphenyl)pent-1-enes
Timmermans, Johan L.,Wamelink, Marc P.,Lodder, Gerrit,Cornelisse, Jan
, p. 463 - 470 (2007/10/03)
Irradiation of a series of 5-(2-methoxyphenyl)pent-1-enes substituted with a hydroxy or trimethylsilyloxy group at the α-, β-, or γ-position of the side-chain yields in all cases meta photocycloadducts, in which the configuration at the substituted carbon atom is mainly endo. This indicates that the diastereoselectivity originates from minimization of steric interactions between the side-chain substituent and the ortho-methoxy group at the arene unit. Hydrogen bonding does not seem to be involved. The introduction of the side-chain substituents also influences the regioselectivity of the addition: The linear to angular adduct ratios are significantly increased compared to the case of the parent compound.
