220466-92-2

Upstream product

• 220467-06-1 [(1R,2R)-2-(2-Benzyloxy-ethyl)-1-methyl-5-methylene-cyclopentyl]-acetonitrile 
• 220467-07-2 [(1R,2R)-2-(2-Benzyloxy-ethyl)-1-methyl-5-methylene-cyclopentyl]-acetaldehyde 
• 220466-90-0 [2-((1R,2R)-2-Bromomethyl-2-methyl-3-methylene-cyclopentyl)-ethoxymethyl]-benzene 
• 13154-24-0 triisopropylsilyl chloride 
• 220467-08-3 2-[(1R,2R)-2-(2-Benzyloxy-ethyl)-1-methyl-5-methylene-cyclopentyl]-ethanol 
• 104758-32-9 (1R,2R)-2-Bromomethyl-1-methoxycarbonylmethyl-2-methyl-3-methylenecyclopentane 
• 99277-05-1 (1R,2R)-2-Bromomethyl-1-(2-hydroxyethyl)-2-methyl-3-methylenecyclopentane 

Downstream Products

• 220467-13-0 (5E,10E)-9-(tert-Butyl-diphenyl-silanyloxy)-12-[(1R,2R)-2-(2-hydroxy-ethyl)-2-methyl-3-methylene-cyclopentyl]-6,10-dimethyl-dodeca-5,10-dien-2-ol 
• 220472-43-5 {(1R,2R)-2-[(2E,7E)-4-(tert-Butyl-diphenyl-silanyloxy)-3,7-dimethyl-11-oxo-dodeca-2,7-dienyl]-1-methyl-5-methylene-cyclopentyl}-acetaldehyde 
• 220467-05-0 tert-Butyl-diphenyl-((5E,10E,14E)-(3aR,16aR)-6,10,14,16a-tetramethyl-1-methylene-1,2,3,3a,4,7,8,9,12,13,16,16a-dodecahydro-cyclopentacyclopentadecen-7-yloxy)-silane 

Relevant academic research and scientific papers

A synthesis of the ring system of terpestacin

The ring system of the sesterterpene terpestacin has been obtained from a cyclopentanic precursor prepared from endo-3-bromocamphor and from an acyclic keto phosphonate prepared from 6-methylhept-5-en-2-one. The connection of both compounds has been achieved by a Horner-Wadsworth-Emmons reaction on the one hand and by a McMurry reaction on the other.