220504-99-4Relevant academic research and scientific papers
The first direct transformation of 2,2'-dihydroxychalcones into coumestans
Kamara, B. Irene,Brandt, E. Vincent,Ferreira, Daneel
, p. 861 - 868 (1999)
Three coumestans, flemichapparin, medicagol and sophoracoumestan B, are synthesised by direct reaction of the analogous 2,2'-dihydroxychalcones with thallium (III) nitrate in methanol.
CHROMENE-4-ONE DERIVATIVES AS BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) MIMETICS
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, (2021/04/01)
The present invention relates to chromen-4-one derivatives comprising a quaternary group, and to associated multi-salts, solvates, prodrugs and pharmaceutical compositions. The present invention also relates to the use of such compounds and compositions in the treatment and prevention of medical disorders and diseases, most especially by modulation of neurotrophic factors (such as BDNF) pathways and modulation of mitochondrial function Formula (I).
