22059-22-9

Usage

Chemical Properties

White crystals

InChI:InChI=1/C2H6N2O/c1-2(3)4-5/h5H,1H3,(H2,3,4)

Upstream product

• 75-05-8 acetonitrile 

Downstream Products

• 807342-24-1 (+)-(3R,4S)-[[4-(4-chlorophenyl)-1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)methylsulfanyl]methyl]piperidine 
• 755029-81-3 N-({3-[3-(3-methoxy-4-nitrophenyI)-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-8-yl]propanoyl}oxy)ethanimidamide 
• 291305-37-8 cis-(1S)-N-methyl-7-(5-(3-methyl-1,2,4-oxadiazolyl))-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 
• 143771-70-4 5-(4'-(2-Butyl-4-chloro-5-(3-methyl-1,2,4-oxadiazol-5-yl)-1-imidazolylmethyl)biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 
• 157695-16-4 3-methyl-5-(4-iodophenyl)-1,2,4-oxadiazole 
• 881028-34-8 [5-(3-methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-yl]-carbamic acid tert-butyl ester 
• 910777-89-8 N-([(8-([(2-ethyl-6-methylphenyl)methyl]amino)-2,3-dimethylimidazo[1,2-a]pyridin-6-yl)carbonyl]oxy)ethanimidamide 
• 705279-08-9 N-[(1Z)-N-hydroxyethanimidoyl]-5-methoxy-2-[(3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]benzamide 
• 496880-45-6 3-(3-Methyl[1,2,4]oxadiazol-5-yl)-6,6-diphenyl-6,7-dihydro-1H-indazole 
• 865706-92-9 3-methyl-5-phenylsulfanylmethyl-[1,2,4]oxadiazole 
• 1170735-87-1 C₂₃H₃₁ClN₆OS 
• 1092113-94-4 (S)-5-[3-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]-9-methylthio-1,2,3,3a,4,5-hexahydro-5,8,10,10b-tetraazabenzo[e]azulen-6-one 
• 1236792-16-7 trans-2-{4-[4-(4-amino-5-oxo-7,8-dihydro-5H-9-oxa-1,3,6-triazabenzocyclohepten-6-yl)phenyl]cyclohexyl}-N-{1-[(E)-hydroxyimino]-ethyl}-acetamide 
• 1236796-02-3 2-((1r,4r)-4-(4-(4-amino-2-methoxy-5-oxo-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)phenyl)cyclohexyl)-N-((Z)-1-(hydroxyimino)ethyl)acetamide 

Relevant academic research and scientific papers

Synthesis of various 3-substituted 1,2,4-oxadiazole-containing chiral β3- and α-amino acids from Fmoc-protected aspartic acid

Various 3-substituted chiral 1,2,4-oxadiazole-containing Fmoc-β 3- and α-amino acids were synthesized from FmoC-(L or D)-Asp(OtBu)-OH and Fmoc-L-Asp-OtBu, respectively, in three steps (i.e., condensation of an aspartyl derivative with different

Synthesis of 3,5-disubstituted-1,2,4-oxadiazoles using tetrabutylammonium fluoride as a mild and efficient catalyst

Tetrabutylammonium fluoride (TBAF) was found to be a mild and efficient catalyst for the synthesis of 3,5-disubstituted-1,2,4-oxadiazoles. Using 0.1 - 1.0 equivalents of TBAF in THF for 1 - 24 h at room temperature, alkanoyl- and aroyloxyamidines were converted in high yield to the corresponding 3,5-disubstituted-1,2,4-oxadiazoles. A variety of R and R′ substituents were investigated.