220604-75-1 Usage
Uses
Used in Pharmaceutical Industry:
1-allyl-3-(4-ethylphenyl)thiourea is utilized as an antithyroid agent for the treatment of hyperthyroidism. It functions by inhibiting the enzyme thyroid peroxidase, which is essential in the synthesis of thyroid hormones, thereby helping to regulate the overproduction of these hormones.
Additionally, it is considered for its potential role in cancer treatment:
1-allyl-3-(4-ethylphenyl)thiourea is explored as a therapeutic agent for certain types of cancer. Its specific biological activities are under investigation to determine its effectiveness and possible mechanisms of action in combating cancer cells.
Used in Agricultural Industry:
1-allyl-3-(4-ethylphenyl)thiourea is also being investigated for its potential use in the development of new pesticides. The unique properties conferred by its allyl and ethylphenyl groups may offer novel pesticidal effects, contributing to advancements in crop protection strategies.
Given the compound's diverse applications and ongoing research, 1-allyl-3-(4-ethylphenyl)thiourea holds promise for future development in both the medical and agricultural sectors, pending further studies to confirm its safety and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 220604-75-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,6,0 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 220604-75:
(8*2)+(7*2)+(6*0)+(5*6)+(4*0)+(3*4)+(2*7)+(1*5)=91
91 % 10 = 1
So 220604-75-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N2S/c1-3-9-13-12(15)14-11-7-5-10(4-2)6-8-11/h3,5-8H,1,4,9H2,2H3,(H2,13,14,15)
220604-75-1Relevant academic research and scientific papers
Synthesis and biological evaluation of arylthiourea derivatives with antitubercular activity
Luo, Rusong,Laitinen, Tuomo,Teng, Liyan,Nevalainen, Tapio,Lahtela-Kakkonen, Maija,Zheng, Baofu,Wang, Honghai,Poso, Antti,Zhang, Xuelian
, p. 640 - 650 (2013/08/23)
Tuberculosis (TB) is a contagious disease caused by Mycobacterium tuberculosis (M. tuberculosis), and remains one of the most life-threatening plagues for public health in the world. The emergence of drug resistant strains of TB and co-infection with HIV has further complicated TB treatment. Here, the synthesis and characterizaton of a series of compounds were described, and these were followed by evaluating for their antibacterial activity against M. tuberculosis. Several novel arylthiourea derivatives exhibited excellent activity (lowest MIC=0.09 μg/ml) against M. tuberculosis including drug resistant strains of M. tuberculosis. The results suggest that these compounds are promising candidates for new anti-TB agent development.
