220615-80-5Relevant articles and documents
IMIDAZOLIDIN-2-ONE COMPOUNDS AS PRMT5 MODULATORS
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Page/Page column 101, (2019/10/15)
The present invention relates to the derivatives of compound of formula (I) and pharmaceutically acceptable salts thereof. The present invention further provides the methods of preparation of compound of formula (I) and use thereof as PRMT5 inhibitors. Th
NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE
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Paragraph 0297; 0298; 0299, (2013/03/26)
Provided are a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2, as well as a prophylactic/therapeutic drug for autoimmune diseases or osteoarthritis. An amide derivative represented by the following formula (I) wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof.