220665-79-2Relevant academic research and scientific papers
Synthesis of phosphoramides for the lewis base-catalyzed allylation and aldol addition reactions
Denmark, Scott E.,Su, Xiping,Nishigaichi, Yutaka,Coe, Diane M.,Wong, Ken-Tsung,Winter, Stephen B. D.,Choi, Jun Young
, p. 1958 - 1967 (2007/10/03)
Both chiral and achiral phosphoramides of diverse structure were prepared from diamines by the coupling to phosphorus(V) or phosphorus(III) reagents. Several enantiopure 1,2-diphenyl-1,2-ethanediamine analogues have been prepared by the reductive coupling of the corresponding N-silylimine with NbCl4(THF)2 and subsequent resolution by the formation of diastereomeric menthyl carbamates. (S,S)-N,N'-Di-(1-naphthyl)-1,2-diphenyl- 1,2-ethanediamine 15 was prepared by the arylation of (S,S)-1,2-diphenyl- 1,2-ethanediamine with naphthyl iodide.
